Literature DB >> 26069489

Using water-soluble C60 fullerenes in anticancer therapy.

S V Prylutska1, A P Burlaka2, P P Klymenko3, I I Grynyuk1, Yu I Prylutskyy1, Ch Schütze4, U Ritter4.   

Abstract

Growth experiments of transplanted malignant tumors in the presence of water-soluble C60 fullerenes were performed on groups of mice. It was found that C60 fullerenes efficiently inhibit the growth of transplanted malignant tumors. This behavior can be explained through their high antioxidant activity and the blocking of the specific cell receptors (for example, endothelial growth factor). The findings demonstrate the possibility of using C60 fullerenes in anticancer therapy.

Entities:  

Keywords:  C60 fullerenes; Histological data; Increasing of animal life; Lewis lung carcinoma; Metastasis inhibition index; Mice line C57Bl/6J; Survival of animals; Tumor growth inhibition

Year:  2011        PMID： 26069489      PMCID： PMC4452036          DOI： 10.1007/s12645-011-0020-x

Source DB:  PubMed          Journal:  Cancer Nanotechnol        ISSN： 1868-6958


  8 in total

Review 1.  Angiogenesis in life, disease and medicine.

Authors:  Peter Carmeliet
Journal:  Nature       Date:  2005-12-15       Impact factor: 49.962

2.  [60]fullerene is a powerful antioxidant in vivo with no acute or subacute toxicity.

Authors:  Najla Gharbi; Monique Pressac; Michelle Hadchouel; Henri Szwarc; Stephen R Wilson; Fathi Moussa
Journal:  Nano Lett       Date:  2005-12       Impact factor: 11.189

3.  Potent angiogenesis inhibition by the particulate form of fullerene derivatives.

Authors:  Huan Meng; Gengmei Xing; Baoyun Sun; Feng Zhao; Hao Lei; Wei Li; Yan Song; Zhen Chen; Hui Yuan; Xuxia Wang; Jing Long; Chunying Chen; Xingjie Liang; Ning Zhang; Zhifang Chai; Yuliang Zhao
Journal:  ACS Nano       Date:  2010-05-25       Impact factor: 15.881

4.  Carbon inhibits vascular endothelial growth factor- and fibroblast growth factor-promoted angiogenesis.

Authors:  Saravanababu Murugesan; Shaker A Mousa; Laura J O'connor; David W Lincoln; Robert J Linhardt
Journal:  FEBS Lett       Date:  2007-02-20       Impact factor: 4.124

Review 5.  The biological mechanisms and physicochemical characteristics responsible for driving fullerene toxicity.

Authors:  Helinor J Johnston; Gary R Hutchison; Frans M Christensen; Karin Aschberger; Vicki Stone
Journal:  Toxicol Sci       Date:  2009-11-09       Impact factor: 4.849

6.  Cellular localisation of a water-soluble fullerene derivative.

Authors:  Sarah Foley; Colin Crowley; Monique Smaihi; Claude Bonfils; Bernard F Erlanger; Patrick Seta; Christian Larroque
Journal:  Biochem Biophys Res Commun       Date:  2002-05-31       Impact factor: 3.575

7.  Inhibition of tumor growth by endohedral metallofullerenol nanoparticles optimized as reactive oxygen species scavenger.

Authors:  Jun-Jie Yin; Fang Lao; Jie Meng; Peter P Fu; Yuliang Zhao; Gengmei Xing; Xueyun Gao; Baoyun Sun; Paul C Wang; Chunying Chen; Xing-Jie Liang
Journal:  Mol Pharmacol       Date:  2008-07-17       Impact factor: 4.436

8.  The scavenging of reactive oxygen species and the potential for cell protection by functionalized fullerene materials.

Authors:  Jun-Jie Yin; Fang Lao; Peter P Fu; Wayne G Wamer; Yuliang Zhao; Paul C Wang; Yang Qiu; Baoyun Sun; Gengmei Xing; Jinquan Dong; Xing-Jie Liang; Chunying Chen
Journal:  Biomaterials       Date:  2008-11-04       Impact factor: 12.479
  8 in total
  7 in total

1.  Interceptor effect of C60 fullerene on the in vitro action of aromatic drug molecules.

Authors:  Galyna B Skamrova; Ivan Laponogov; Anatoly S Buchelnikov; Yuriy G Shckorbatov; Svitlana V Prylutska; Uwe Ritter; Yuriy I Prylutskyy; Maxim P Evstigneev
Journal:  Eur Biophys J       Date:  2014-04-20       Impact factor: 1.733

2.  C60 fullerene as synergistic agent in tumor-inhibitory Doxorubicin treatment.

Authors:  Svitlana Prylutska; Iryna Grynyuk; Olga Matyshevska; Yuriy Prylutskyy; Maxim Evstigneev; Peter Scharff; Uwe Ritter
Journal:  Drugs R D       Date:  2014-12

3.  Suppression of synaptic plasticity by fullerenol in rat hippocampus in vitro.

Authors:  Xin-Xing Wang; Ying-Ying Zha; Bo Yang; Lin Chen; Ming Wang
Journal:  Int J Nanomedicine       Date:  2016-09-28

4.  Comparative Analysis of the Antineoplastic Activity of C60 Fullerene with 5-Fluorouracil and Pyrrole Derivative In Vivo.

Authors:  O V Lynchak; Yu I Prylutskyy; V K Rybalchenko; O A Kyzyma; D Soloviov; V V Kostjukov; M P Evstigneev; U Ritter; P Scharff
Journal:  Nanoscale Res Lett       Date:  2017-01-05       Impact factor: 4.703

5.  C60 fullerene and its nanocomplexes with anticancer drugs modulate circulating phagocyte functions and dramatically increase ROS generation in transformed monocytes.

Authors:  Larysa M Skivka; Svitlana V Prylutska; Mariia P Rudyk; Nataliia M Khranovska; Ievgeniia V Opeida; Vasyl V Hurmach; Yuriy I Prylutskyy; Leonid F Sukhodub; Uwe Ritter
Journal:  Cancer Nanotechnol       Date:  2018-10-31

6.  Synthesis of C60 Fullerene-Quadricyclane Hybrid Compound and Its Preliminary In Vitro Antitumor Activity in Combination with Cisplatin.

Authors:  Usein M Dzhemilev; Artur A Khuzin; Arslan R Akhmetov; Vladimir A D'yakonov; Lilya U Dzhemileva; Milyausha M Yunusbaeva; Airat R Tuktarov
Journal:  ACS Omega       Date:  2019-09-20

Review 7.  Nanoparticle-Mediated Combination Therapy: Two-in-One Approach for Cancer.

Authors:  Sangiliyandi Gurunathan; Min-Hee Kang; Muhammad Qasim; Jin-Hoi Kim
Journal:  Int J Mol Sci       Date:  2018-10-20       Impact factor: 5.923
  7 in total

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