Literature DB >> 26068568

Ghrelin in Critical Illness.

Tathagat Narula1,2, Bennett P deBoisblanc3.   

Abstract

Ghrelin, a recently described peptide, has attracted significant attention in recent years, primarily in the context of its endocrine- and appetite-regulating effects. The versatility of this peptide is manifested in a rapidly expanding body of literature highlighting its nonendocrine functions. This review summarizes the available data on the immunomodulatory as well as the non-immune-mediated effects of ghrelin that form the scientific basis of its role in critical illness.

Entities:  

Keywords:  cytokines; ghrelin; immunity; leptin; sepsis

Mesh：

Substances：

Year:  2015        PMID： 26068568     DOI： 10.1165/rcmb.2014-0226TR

Source DB:  PubMed          Journal:  Am J Respir Cell Mol Biol        ISSN： 1044-1549            Impact factor:   6.914


  12 in total

1.  Therapeutic effect of human ghrelin and growth hormone: Attenuation of immunosuppression in septic aged rats.

Authors:  Mian Zhou; Weng-Lang Yang; Monowar Aziz; Gaifeng Ma; Ping Wang
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2017-01-20       Impact factor: 5.187

2.  Shikonin induces apoptosis of lung cancer cells via activation of FOXO3a/EGR1/SIRT1 signaling antagonized by p300.

Authors:  Yun-Ji Jeung; Han-Gyeul Kim; Jiwon Ahn; Ho-Joon Lee; Sae-Bhom Lee; Misun Won; Cho-Rock Jung; Joo-Young Im; Bo-Kyung Kim; Seung-Kiel Park; Myung Jin Son; Kyung-Sook Chung
Journal:  Biochim Biophys Acta       Date:  2016-07-21

3.  The protective role of human ghrelin in sepsis: Restoration of CD4 T cell proliferation.

Authors:  Mian Zhou; Monowar Aziz; Manhendar Ochani; Weng-Lang Yang; Archna Sharma; Ping Wang
Journal:  PLoS One       Date:  2018-07-27       Impact factor: 3.240

Review 4.  Ghrelin as an Anti-Sepsis Peptide: Review.

Authors:  Nimisha Mathur; Syed F Mehdi; Manasa Anipindi; Monowar Aziz; Sawleha A Khan; Hema Kondakindi; Barbara Lowell; Ping Wang; Jesse Roth
Journal:  Front Immunol       Date:  2021-01-28       Impact factor: 7.561

5.  Diagnostic Accuracy of Plasma Ghrelin Concentrations in Pediatric Sepsis-Associated Acute Respiratory Distress Syndrome: A Single-Center Cohort Study.

Authors:  Xiu Yuan; Shaojun Li; Liang Zhou; Tian Tang; Yuwei Cheng; Xiaoxiao Ao; Liping Tan
Journal:  Front Pediatr       Date:  2021-05-21       Impact factor: 3.418

6.  Serum ghrelin, but not obestatin, is a potential predictor of acute pancreatitis severity.

Authors:  Huilin Wang; Mengbin Qin; Zhihai Liang; Renjie Chang; Hongzong Fu; Yule Wei; Guodu Tang
Journal:  Medicine (Baltimore)       Date:  2017-09       Impact factor: 1.889

7.  Correction of immunosuppression in aged septic rats by human ghrelin and growth hormone through the vagus nerve-dependent inhibition of TGF-β production.

Authors:  Mian Zhou; Monowar Aziz; Mahendar Ochani; Ping Wang
Journal:  Mol Med       Date:  2020-07-16       Impact factor: 6.354

8.  The association between the route of nutrition and serum levels of adipokines in critical illness: a pilot study.

Authors:  Kürşat Gündoğan; Ender Doğan; Nurhayat Tuğra Özer; Gülşah Güneş Şahin; Serap Şahin; Murat Sungur; Ismail Hakki Akbudak; Sabahattin Muhtaroğlu; Muhammet Güven; Thomas R Ziegler
Journal:  Turk J Med Sci       Date:  2020-04-27       Impact factor: 0.973

9.  Relationships between Ghrelin and Obestatin with MDA, Proinflammatory Cytokines, GSH/GSSG Ratio, Catalase Activity, and Semen Parameters in Infertile Patients with Leukocytospermia and Varicocele.

Authors:  Lucia Micheli; Giulia Collodel; Daniela Cerretani; Andrea Menchiari; Daria Noto; Cinzia Signorini; Elena Moretti
Journal:  Oxid Med Cell Longev       Date:  2019-10-21       Impact factor: 6.543

10.  A Suggested Role of Human Growth Hormone in Control of the COVID-19 Pandemic.

Authors:  Mohamed Hamdy Elkarow; Amr Hamdy
Journal:  Front Endocrinol (Lausanne)       Date:  2020-11-09       Impact factor: 5.555
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