Literature DB >> 26067082

Rapid method for growth hormone receptor exon 3 delete (GHRd3) SNP genotyping from archival human placental samples.

Rebecca A Pelekanos1, Varda S Sardesai, Marloes Dekker Nitert, Leonie K Callaway, Nicholas M Fisk, Penny L Jeffery.   

Abstract

Analysis of archival samples from cohorts of pregnant women may be key to discovering prognosticators of stillbirth and pregnancy/perinatal complications. Growth hormone (GH) and its receptor (GHR) are pivotal in feto-placental development and pregnancy maintenance. We report a rapid, optimized method for genotyping the GHR full-length versus exon 3-deleted isoform (GHRd3). TaqMan single nucleotide polymorphism (SNP) genotyping proved superior to standard multiplex polymerase chain reaction (PCR) in allele detection and GHR genotyping from archived samples, including those with poor genomic deoxyribonucleic acid quality/quantity such as formalin fixed, paraffin embedded, blood, and serum. Furthermore, this assay is suitable for high through put 96 or 384-well plate quantitative PCR machines with automated genotype calling software. The TaqMan genotyping assay can increase the data obtained from precious archival human samples.

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Year:  2015        PMID： 26067082     DOI： 10.1007/s12020-015-0647-1

Source DB:  PubMed          Journal:  Endocrine        ISSN： 1355-008X            Impact factor:   3.633


  48 in total

1.  Model for growth hormone receptor activation based on subunit rotation within a receptor dimer.

Authors:  Richard J Brown; Julian J Adams; Rebecca A Pelekanos; Yu Wan; William J McKinstry; Kathryn Palethorpe; Ruth M Seeber; Thea A Monks; Karin A Eidne; Michael W Parker; Michael J Waters
Journal:  Nat Struct Mol Biol       Date:  2005-08-21       Impact factor: 15.369

2.  Comparison of human placenta- and bone marrow-derived multipotent mesenchymal stem cells.

Authors:  Sarah Barlow; Gary Brooke; Konica Chatterjee; Gareth Price; Rebecca Pelekanos; Tony Rossetti; Marylou Doody; Deon Venter; Scott Pain; Kristen Gilshenan; Kerry Atkinson
Journal:  Stem Cells Dev       Date:  2008-12       Impact factor: 3.272

3.  The d3-growth hormone (GH) receptor polymorphism is associated with increased responsiveness to GH in Turner syndrome and short small-for-gestational-age children.

Authors:  G Binder; F Baur; R Schweizer; M B Ranke
Journal:  J Clin Endocrinol Metab       Date:  2005-11-15       Impact factor: 5.958

4.  Mechanism of activation of protein kinase JAK2 by the growth hormone receptor.

Authors:  Andrew J Brooks; Wei Dai; Megan L O'Mara; Daniel Abankwa; Yash Chhabra; Rebecca A Pelekanos; Olivier Gardon; Kathryn A Tunny; Kristopher M Blucher; Craig J Morton; Michael W Parker; Emma Sierecki; Yann Gambin; Guillermo A Gomez; Kirill Alexandrov; Ian A Wilson; Manolis Doxastakis; Alan E Mark; Michael J Waters
Journal:  Science       Date:  2014-05-16       Impact factor: 47.728

5.  Evaluation of five DNA extraction methods for detection of H. pylori in formalin-fixed paraffin-embedded (FFPE) liver tissue from patients with hepatocellular carcinoma.

Authors:  Elizabeth Rabelo-Gonçalves; Bruna Roesler; Ana Carolina Guardia; Arlete Milan; Natalicia Hara; Cecília Escanhoela; Jazon Almeida; Ilka Boin; José Murilo Zeitune
Journal:  Pathol Res Pract       Date:  2013-11-15       Impact factor: 3.250

6.  The exon 3-deleted/full-length growth hormone receptor polymorphism and response to growth hormone therapy in growth hormone deficiency and Turner syndrome: a multicenter study.

Authors:  Firdevs Baş; Feyza Darendeliler; Zehra Aycan; Ergun Çetinkaya; Merih Berberoğlu; Zeynep Sıklar; Gönül Öcal; Özlem Timirci; Semra Çetinkaya; Şükran Darcan; Damla Gökşen Şimşek; Aysun Bideci; Peyami Cinaz; Ece Böber; Korcan Demir; Abdullah Bereket; Serap Turan; M Emre Atabek; Filiz Tütüncüler; Turgay Isbir; Nilüfer Bozkurt; Sema Kabataş Eryılmaz; Ozan Uzunhan; Banu Küçükemre Aydın; Rüveyde Bundak
Journal:  Horm Res Paediatr       Date:  2012-03-23       Impact factor: 2.852

7.  The exon 3 polymorphism of the growth hormone receptor is a severity-related factor for osteoporosis.

Authors:  Felipe Albuquerque Marques; Túlio Cesar Lins; Ricardo Moreno Lima; Rômulo Maia Carlos Fonseca; Nanci Maria de França; Ricardo Jacó de Oliveira; Maria Teresinha de Oliveira Cardoso; Rinaldo Wellerson Pereira; Robert Pogue
Journal:  Endocrine       Date:  2013-06-28       Impact factor: 3.633

8.  The common exon 3 polymorphism of the growth hormone receptor gene and the effect of growth hormone therapy on growth in Korean patients with Turner syndrome.

Authors:  Jung Min Ko; Jae-Min Kim; Chong-Kun Cheon; Duk-Hee Kim; Dae-Yeol Lee; Woo Yeong Cheong; Eun Young Kim; Mi Jung Park; Han-Wook Yoo
Journal:  Clin Endocrinol (Oxf)       Date:  2009-08-04       Impact factor: 3.478

9.  Association of fetal-derived hypermethylated RASSF1A concentration in placenta-mediated pregnancy complications.

Authors:  M J Kim; S Y Kim; S Y Park; H K Ahn; J H Chung; H M Ryu
Journal:  Placenta       Date:  2012-11-24       Impact factor: 3.481

10.  The growth hormone receptor gene deleted for exon three (GHRd3) polymorphism is associated with birth and placental weight.

Authors:  Raja Padidela; Sinead M Bryan; Sayeda Abu-Amero; Rebecca E Hudson-Davies; John C Achermann; Gudrun E Moore; Peter C Hindmarsh
Journal:  Clin Endocrinol (Oxf)       Date:  2012-02       Impact factor: 3.478
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  2 in total

1.  A descriptive study on selected growth parameters and growth hormone receptor gene in healthy young adults from the American Midwest.

Authors:  Samantha N Hartin; Waheeda A Hossain; Ann M Manzardo; Shaquanna Brown; Paula J Fite; Marco Bortolato; Merlin G Butler
Journal:  Growth Horm IGF Res       Date:  2018-02-12       Impact factor: 2.372

2.  Avoidance of Maternal Cell Contamination and Overgrowth in Isolating Fetal Chorionic Villi Mesenchymal Stem Cells from Human Term Placenta.

Authors:  Varda S Sardesai; Abbas Shafiee; Nicholas M Fisk; Rebecca A Pelekanos
Journal:  Stem Cells Transl Med       Date:  2017-02-16       Impact factor: 6.940
  2 in total

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