Literature DB >> 26066846

Design and synthesis of active heparan sulfate-based probes.

Wen Zhou1,2, Po-Hung Hsieh1, Yongmei Xu1, Timothy R O'Leary1, Xuefei Huang3, Jian Liu1.   

Abstract

A chemoenzymatic approach for synthesizing heparan sulfate oligosaccharides with a reactive diazoacetyl saccharide residue is reported. The resultant oligosaccharides were demonstrated to serve as specific inhibitors for heparan sulfate sulfotransferases, offering a new set of tools to probe the structural selectivity for heparan sulfate-binding proteins.

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Year:  2015        PMID： 26066846      PMCID： PMC4502442          DOI： 10.1039/c5cc02008e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

Review 1.  Irreversible inhibitors of serine, cysteine, and threonine proteases.

Authors:  James C Powers; Juliana L Asgian; Ozlem Dogan Ekici; Karen Ellis James
Journal:  Chem Rev       Date:  2002-12       Impact factor: 60.622

Review 2.  Demystifying heparan sulfate-protein interactions.

Authors:  Ding Xu; Jeffrey D Esko
Journal:  Annu Rev Biochem       Date:  2014-03-06       Impact factor: 23.643

3.  Dissecting the substrate recognition of 3-O-sulfotransferase for the biosynthesis of anticoagulant heparin.

Authors:  Andrea F Moon; Yongmei Xu; Susan M Woody; Joseph M Krahn; Robert J Linhardt; Jian Liu; Lars C Pedersen
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-19       Impact factor: 11.205

Review 4.  Cell surface heparan sulfate and its roles in assisting viral infections.

Authors:  Jian Liu; Suzanne C Thorp
Journal:  Med Res Rev       Date:  2002-01       Impact factor: 12.944

Review 5.  Understanding the substrate specificity of the heparan sulfate sulfotransferases by an integrated biosynthetic and crystallographic approach.

Authors:  Jian Liu; Andrea F Moon; Juzheng Sheng; Lars C Pedersen
Journal:  Curr Opin Struct Biol       Date:  2012-07-26       Impact factor: 6.809

6.  Molecular mechanism of substrate specificity for heparan sulfate 2-O-sulfotransferase.

Authors:  Chunhui Liu; Juzheng Sheng; Juno M Krahn; Lalith Perera; Yongmei Xu; Po-Hung Hsieh; Wenfang Dou; Jian Liu; Lars C Pedersen
Journal:  J Biol Chem       Date:  2014-03-20       Impact factor: 5.157

7.  Hs3st3-modified heparan sulfate controls KIT+ progenitor expansion by regulating 3-O-sulfotransferases.

Authors:  Vaishali N Patel; Isabelle M A Lombaert; Samuel N Cowherd; Nicholas W Shworak; Yongmei Xu; Jian Liu; Matthew P Hoffman
Journal:  Dev Cell       Date:  2014-06-23       Impact factor: 12.270

8.  Matrix-IR spectroscopic investigations of the thermolysis and photolysis of diazoamides.

Authors:  Curt Wentrup; Hervé Bibas; Arvid Kuhn; Ullrich Mitschke; Mark C McMills
Journal:  J Org Chem       Date:  2013-10-24       Impact factor: 4.354

Review 9.  Chemoenzymatic synthesis of heparan sulfate and heparin.

Authors:  Jian Liu; Robert J Linhardt
Journal:  Nat Prod Rep       Date:  2014-09-08       Impact factor: 13.423

Review 10.  Interactions between heparan sulfate and proteins: the concept of specificity.

Authors:  Johan Kreuger; Dorothe Spillmann; Jin-ping Li; Ulf Lindahl
Journal:  J Cell Biol       Date:  2006-07-31       Impact factor: 10.539
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  2 in total

Review 1.  Diazo Compounds: Versatile Tools for Chemical Biology.

Authors:  Kalie A Mix; Matthew R Aronoff; Ronald T Raines
Journal:  ACS Chem Biol       Date:  2016-10-26       Impact factor: 5.100

2.  Rapid cycloaddition of a diazo group with an unstrained dipolarophile.

Authors:  Matthew R Aronoff; Brian Gold; Ronald T Raines
Journal:  Tetrahedron Lett       Date:  2016-04-28       Impact factor: 2.415
  2 in total

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