| Literature DB >> 26065423 |
Shari Wynd, Michael Westaway, Sunita Vohra, Greg Kawchuk.
Abstract
Entities:
Year: 2015 PMID: 26065423 PMCID: PMC4466799 DOI: 10.1371/journal.pone.0129991
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Fig 2Overall Meta-analysis on the VAS Scores.
Patients receiving ALC showed significantly more reduction in VAS scores than those receiving placebo. The values presented referred to the change of VAS scores from baseline. VAS = Visual Analogue Scale; ALC = acetyl-l-carnitine; UCE = U.S.-CanadianEuropean Study; UC = U.S.-Canadian Study; SD = standard deviation; CI = confidence interval.
Fig 3Subgroup-analysis on the VAS Scores of the Diabetic and Non-diabetic Patients.
Subgroup-analysis was performed by subdividing RCTs according to whether the peripheral neuropathy diagnosed in patients was diabetic or non-diabetic. Taking ALC decreased VAS scores significantly in diabetic patients. VAS = Visual Analogue Scale; ALC = acetyl-l-carnitine; UCE = U.S.-Canadian-European Study; UC = U.S.-Canadian Study; SD = standard deviation; CI = confidence interval.
Fig 4Subgroup-analysis on the VAS Scores by Subdividing RCTs according to the Route of Administration.
Oral administration of ALC decreased VAS scores significantly. VAS = Visual Analogue Scale; ALC = acetyl-l-carnitine; UCE = U.S.-Canadian-European Study; UC = U.S.-Canadian Study; SD = standard deviation; CI = confidence interval.