Literature DB >> 26064401

Surgical treatment for locally advanced pancreatic cancer localized in the pancreatic body and tail (report of 11 cases).

Zhonglian Li1, Haitao Shang1, Xibo Zhang1, Hongtao Zhang1, Jianheng Bao1, Chengfei Hao1.   

Abstract

OBJECTIVE: To investigate the clinical efficacy of radical resection for pancreatic cancer localized in the pancreatic body and tail.
METHODS: From 2009 to 2013, 11 patients with pancreatic cancer localized in the body and tail were treated with sequential radical resection of the tumor and postoperative chemotherapy, and closely followed up.
RESULTS: Among the 11 patients, 7 received R0 resection, 4 received R1 resection. In the rest 2 patients, the tumor was removed together with the involved celiac artery and common hepatic artery. There were no postoperative complications, except second surgery for postoperative ischemic necrosis of the gastric antrum in 1 case, and wound infection in another patient. Nine of the 11 patients underwent cyclic chemotherapy with gemcitabine. Abdominal pain was relieved in all postoperative patients. The postoperative median survival time was 28 months, and 1-year and 3-year survival rates were 81.8% and 36.3%, respectively.
CONCLUSION: Combination of surgical removal of the tumor with adjuvant chemotherapy can achieve better survival and significantly improve the patients' quality of life.

Entities:  

Keywords:  Pancreatic cancer; chemotherapy; radical resection

Year:  2015        PMID: 26064401      PMCID: PMC4443235     

Source DB:  PubMed          Journal:  Int J Clin Exp Med        ISSN: 1940-5901


  8 in total

1.  Diagnostic imaging for pancreatic cancer: computed tomography, magnetic resonance imaging, and positron emission tomography.

Authors:  Hiromitsu Saisho; Taketo Yamaguchi
Journal:  Pancreas       Date:  2004-04       Impact factor: 3.327

2.  The value of splenic preservation with distal pancreatectomy.

Authors:  Margo Shoup; Murray F Brennan; Kertrisa McWhite; Denis H Y Leung; David Klimstra; Kevin C Conlon
Journal:  Arch Surg       Date:  2002-02

3.  Pancreatic cancer in England and Wales 1975-2000: patterns and trends in incidence, survival and mortality.

Authors:  H E Wood; S Gupta; J Y Kang; M J Quinn; J D Maxwell; S Mudan; A Majeed
Journal:  Aliment Pharmacol Ther       Date:  2006-04-15       Impact factor: 8.171

4.  Pancreatic Cancer Registry in Japan: 20 years of experience.

Authors:  Seiki Matsuno; Shinichi Egawa; Shoji Fukuyama; Fuyuhiko Motoi; Makoto Sunamura; Shuji Isaji; Toshihide Imaizumi; Shuichi Okada; Hiroyuki Kato; Kouichi Suda; Akimasa Nakao; Takehisa Hiraoka; Ryo Hosotani; Kazunori Takeda
Journal:  Pancreas       Date:  2004-04       Impact factor: 3.327

5.  En bloc vascular resection for locally advanced pancreatic malignancies infiltrating major blood vessels: perioperative outcome and long-term survival in 136 patients.

Authors:  Emre F Yekebas; Dean Bogoevski; Guellue Cataldegirmen; Christina Kunze; Andreas Marx; Yogesh K Vashist; Paulus G Schurr; Lena Liebl; Sabrina Thieltges; Karim A Gawad; Claus Schneider; Jakob R Izbicki
Journal:  Ann Surg       Date:  2008-02       Impact factor: 12.969

6.  Pancreatic cancer with paraaortic lymph node metastasis: a contraindication for radical surgery?

Authors:  Suguru Yamada; Akimasa Nakao; Tsutomu Fujii; Hiroyuki Sugimoto; Naohito Kanazumi; Shuji Nomoto; Yasuhiro Kodera; Shin Takeda
Journal:  Pancreas       Date:  2009-01       Impact factor: 3.327

7.  Morphological lesions associated with human primary invasive nonendocrine pancreas cancer.

Authors:  A L Cubilla; P J Fitzgerald
Journal:  Cancer Res       Date:  1976-07       Impact factor: 12.701

8.  Phase III trial comparing intensive induction chemoradiotherapy (60 Gy, infusional 5-FU and intermittent cisplatin) followed by maintenance gemcitabine with gemcitabine alone for locally advanced unresectable pancreatic cancer. Definitive results of the 2000-01 FFCD/SFRO study.

Authors:  B Chauffert; F Mornex; F Bonnetain; P Rougier; C Mariette; O Bouché; J F Bosset; T Aparicio; L Mineur; A Azzedine; P Hammel; J Butel; N Stremsdoerfer; P Maingon; L Bedenne
Journal:  Ann Oncol       Date:  2008-05-07       Impact factor: 32.976

  8 in total
  2 in total

1.  Complete Response after Treatment with Neoadjuvant Chemoradiation with Prolonged Chemotherapy for Locally Advanced, Unresectable Adenocarcinoma of the Pancreas.

Authors:  Tiffany A Pompa; William F Morano; Chetan Jeurkar; Hui Li; Suganthi Soundararajan; Jaganmohan Poli; Wilbur B Bowne; Michael Styler
Journal:  Case Rep Oncol Med       Date:  2017-03-08

Review 2.  MicroRNAs in Pancreatic Cancer: biomarkers, prognostic, and therapeutic modulators.

Authors:  Afra Z Daoud; Eoghan J Mulholland; Grace Cole; Helen O McCarthy
Journal:  BMC Cancer       Date:  2019-11-21       Impact factor: 4.430

  2 in total

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