Literature DB >> 26064366

Investigation on the genomic diversity of OXA from isolated Acinetobacter baumannii.

Zhen Ma1, Luqiu Zhou2, Hui Wang3, Liangping Luo4.   

Abstract

We distinguished the four alleles of OXA subgroups from 138 strains of Acinetobacter baumannii using Polymerase Chain Reaction, and investigated distributions of OXA subgroups in clinical isolated strains. A total of 170 Acinetobacter baumannii were isolated from Shenzhen Longgang Central Hospital between 2010 and 2013. Amplification of OXA genes, blaOXA-23, blaOXA-24, blaOXA-51 and blaOXA-58, were performed by multiplex PCR. Multiplex PCR results showed, out of the 96 strains of Acinetobacter baumannii, 50 (52.08%) strains were positive for only blaOXA51 gene, and 46 (47.92%) showed positive for both blaOXA51 and blaOXA58 genes. Among 96 strains of Acinetobacter baumannii, 48 strains were resistant to carbapenems, and 48 strains were sensitivity to carbapenems. blaOXA51 and blaOXA58 showed resistant or sensitivity to carbapenems. In conclusion, we found that blaOXA-51 and blaOXA-5 were the main mechanisms of resistant or sensitivity to carbapenems.

Entities:  

Keywords:  Acinetobacter baumannii; Genomic diversity; OXA

Year:  2015        PMID： 26064366      PMCID： PMC4443200     

Source DB:  PubMed          Journal:  Int J Clin Exp Med        ISSN： 1940-5901


  13 in total

1.  Emergence of carbapenem-resistant Acinetobacter in a temperate north Indian State.

Authors:  N K Bali; B A Fomda; H Bashir; D Zahoor; S Lone; P A Koul
Journal:  Br J Biomed Sci       Date:  2013       Impact factor: 3.829

2.  Sequential outbreaks in a Spanish hospital caused by multiresistant OXA-58-producing Acinetobacter baumannii ST92.

Authors:  Jorge Julio Cabrera Alvargonzalez; Ana Vindel Hernando; Maria Dolores Rojo Martín; Consuelo Miranda Casas; Jesús Oteo Iglesias; Mari Fe Bautista Marín; Maria Luisa Azañedo Alvarez; Veronica Bautista Sanchez; Jose Maria Navarro Marí
Journal:  J Med Microbiol       Date:  2014-05-27       Impact factor: 2.472

3.  Molecular detection of OXA carbapenemase genes in multidrug-resistant Acinetobacter baumannii isolates from Iraq and Georgia.

Authors:  Ia Kusradze; Seydina M Diene; Marina Goderdzishvili; Jean-Marc Rolain
Journal:  Int J Antimicrob Agents       Date:  2011-05-26       Impact factor: 5.283

4.  Clonal diversity and high prevalence of OXA-58 among Acinetobacter baumannii isolates from blood cultures in a tertiary care centre in Turkey.

Authors:  Gokhan Metan; Fatma Sariguzel; Bulent Sumerkan; Tanny van der Reijden; Lenie Dijkshoorn
Journal:  Infect Genet Evol       Date:  2012-12-01       Impact factor: 3.342

5.  Genetic diversity of OXA-51-like genes among multidrug-resistant Acinetobacter baumannii in Riyadh, Saudi Arabia.

Authors:  M Aly; H T Tayeb; S M Al Johani; E J Alyamani; F Aldughaishem; I Alabdulkarim; H H Balkhy
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-02-10       Impact factor: 3.267

6.  A retrospective analysis of carbapenem-resistant Acinetobacter baumannii-mediated nosocomial pneumonia and the in vitro therapeutic benefit of cefoperazone/sulbactam.

Authors:  Jingjing Xia; Duchao Zhang; Yaping Xu; Meiliang Gong; Yu Zhou; Xiangqun Fang
Journal:  Int J Infect Dis       Date:  2014-04-12       Impact factor: 3.623

7.  Mechanisms of resistance to carbapenems in meropenem- resistant Acinetobacter isolates from clinical samples.

Authors:  M Sinha; H Srinivasa
Journal:  Indian J Med Microbiol       Date:  2007-04       Impact factor: 0.985

8.  Differences in carbapenem resistance genes among Acinetobacterbaumannii, Acinetobacter genospecies 3 and Acinetobacter genospecies 13TU in Taiwan.

Authors:  Yu-Chi Lin; Wang-Huei Sheng; Yee-Chun Chen; Shan-Chwen Chang; Ko-Chiang Hsia; Shu-Ying Li
Journal:  Int J Antimicrob Agents       Date:  2010-01-27       Impact factor: 5.283

9.  An outbreak of Acinetobacter respiratory tract infection resulting from incomplete disinfection of ventilatory equipment.

Authors:  C Cefai; J Richards; F K Gould; P McPeake
Journal:  J Hosp Infect       Date:  1990-02       Impact factor: 3.926

10.  Antimicrobial susceptibility profiling and genomic diversity of Acinetobacter baumannii isolates: A study in western Iran.

Authors:  Parviz Mohajeri; Abbas Farahani; Mohammad Mehdi Feizabadi; Hosnieh Ketabi; Ramin Abiri; Farid Najafi
Journal:  Iran J Microbiol       Date:  2013-09
View more
  3 in total

1.  Epidemiology and resistance features of Acinetobacter baumannii isolates from the ward environment and patients in the burn ICU of a Chinese hospital.

Authors:  Yali Gong; Xiaodong Shen; Guangtao Huang; Cheng Zhang; Xiaoqiang Luo; Supeng Yin; Jing Wang; Fuquan Hu; Yizhi Peng; Ming Li
Journal:  J Microbiol       Date:  2016-08-02       Impact factor: 3.422

2.  Carbapenem resistant Pseudomonas aeruginosa and Acinetobacter baumannii at Mulago Hospital in Kampala, Uganda (2007-2009).

Authors:  David P Kateete; Ritah Nakanjako; Juliet Namugenyi; Joseph Erume; Moses L Joloba; Christine F Najjuka
Journal:  Springerplus       Date:  2016-08-09

3.  Diversity and Antibiotic Susceptibility of Acinetobacter Strains From Milk Powder Produced in Germany.

Authors:  Gyu-Sung Cho; Bo Li; André Rostalsky; Gregor Fiedler; Niels Rösch; Etinosa Igbinosa; Jan Kabisch; Wilhelm Bockelmann; Philipp Hammer; Geert Huys; Charles M A P Franz
Journal:  Front Microbiol       Date:  2018-03-27       Impact factor: 5.640
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.