Literature DB >> 26064323

Preoperative CRP levels is not predictive early renal dysfunction after coronary artery bypass surgery.

Veysel Sahin1, Mehmet Besir Akpinar1, Erol Sevim2, Ihsan Sami Uyar1, Ahmet Feyzi Abacilar1, Halil Uc1, Funda Tetik1, Ertan Damar3, Faik Fevzi Okur1, Emin Alp Alayunt1.   

Abstract

BACKGROUND: The aim of this retrospective study is to determine the correlation between preoperative CRP levels and the early renal dysfunction after cardiac surgery.
METHODS: From January 2012 to December 2013, values for preoperative CRP were available for 546 unselected patients undergoing cardiac operations. CRP was used to divide this cohort in two groups: a normal CRP levels group (Group I) of 432 patients with CRP of less than 0.5 mg/dL, and a high CRP levels group (group II) of 114 patients with a CRP of 0.5 mg/dL or more.
RESULTS: Median CRP preoperative values were significantly different in the group II (2.49±1.03 mg/dL) than in the group I (0.32±0.14 mg/dL; P < 0.0001). Median CRP postoperative values were significantly different in the group I (17.62±2.99) than in the group II (23.13±3.01; P < 0.0001). Preoperative levels of serum blood urea nitrogen (BUN), creatinine and CrCl were not significantly different between group I and group II. Postoperative levels of BUN, Cr and CrCl between the two groups were not significantly different.
CONCLUSIONS: The early Cr and CrCl levels after surgery are not significantly different in group I and group II. The early renal function after CABG is not correlated with the preoperative CRP levels.

Entities:  

Keywords:  C-reactive protein; cardiopulmonary bypass; renal function

Year:  2015        PMID: 26064323      PMCID: PMC4443157     

Source DB:  PubMed          Journal:  Int J Clin Exp Med        ISSN: 1940-5901


  21 in total

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