Literature DB >> 26064308

Assessment of total cardiac repolarization's spatial distribution among patients with aortic sclerosis.

Oguzhan Ekrem Turan1, Mustafa Ozturk2, Abdulselam Ilter3, Mustafa Inc4, Kayihan Karaman5, Gulhanim Kiris6, Merih Kutlu4.   

Abstract

OBJECTIVE: To measure the Tp-e value, which shows the spatial distribution of cardiac repolarization and is defined as a possible predictor for ventricular arrhythmia among patients with aortic sclerosis (AS), and to compare this parameter's length to QTc length within the same population.
METHOD: 60 patients that have been diagnosed with AS have been prospectively included in this study.
RESULTS: 60 AS and 64 control patients were evaluated as part of the study. The median age, prevalence for hypertension and diabetes, baseline medications and laboratory results of the groups were similar. The Electrocardiographic QT length of both groups were found similar. In the AS group Tp-e tangent and Tp-e tail values were more longer than control group (P < 0.001). Tp-e tangent index and Tp-e tail index values were also statistically higher among AS patients when compared to the control group. (P < 0.001).
CONCLUSION: Our study showed that Tp-e durations had increased in AS patients with no structural coronary heart disease. AS causes local degeneration on the aortic root and also has a negative effect on the total cardiac spatial repolarization.

Entities:  

Keywords:  Aortic sclerosis; cardiac repolarization

Year:  2015        PMID: 26064308      PMCID: PMC4443142     

Source DB:  PubMed          Journal:  Int J Clin Exp Med        ISSN: 1940-5901


  23 in total

Review 1.  The M cell: its contribution to the ECG and to normal and abnormal electrical function of the heart.

Authors:  C Antzelevitch; W Shimizu; G X Yan; S Sicouri; J Weissenburger; V V Nesterenko; A Burashnikov; J Di Diego; J Saffitz; G P Thomas
Journal:  J Cardiovasc Electrophysiol       Date:  1999-08

Review 2.  Spectrum of calcific aortic valve disease: pathogenesis, disease progression, and treatment strategies.

Authors:  Rosario V Freeman; Catherine M Otto
Journal:  Circulation       Date:  2005-06-21       Impact factor: 29.690

3.  Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice.

Authors:  Helmut Baumgartner; Judy Hung; Javier Bermejo; John B Chambers; Arturo Evangelista; Brian P Griffin; Bernard Iung; Catherine M Otto; Patricia A Pellikka; Miguel Quiñones
Journal:  J Am Soc Echocardiogr       Date:  2009-01       Impact factor: 5.251

4.  Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome.

Authors:  G X Yan; C Antzelevitch
Journal:  Circulation       Date:  1998-11-03       Impact factor: 29.690

5.  Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study.

Authors:  B F Stewart; D Siscovick; B K Lind; J M Gardin; J S Gottdiener; V E Smith; D W Kitzman; C M Otto
Journal:  J Am Coll Cardiol       Date:  1997-03-01       Impact factor: 24.094

6.  In vivo validation of the coincidence of the peak and end of the T wave with full repolarization of the epicardium and endocardium in swine.

Authors:  Yunlong Xia; Yanchun Liang; Ole Kongstad; Qiuming Liao; Magnus Holm; Bertil Olsson; Shiwen Yuan
Journal:  Heart Rhythm       Date:  2005-02       Impact factor: 6.343

7.  Prolonged Tpeak-to-tend interval on the resting ECG is associated with increased risk of sudden cardiac death.

Authors:  Ragesh Panikkath; Kyndaron Reinier; Audrey Uy-Evanado; Carmen Teodorescu; Jonathan Hattenhauer; Ronald Mariani; Karen Gunson; Jonathan Jui; Sumeet S Chugh
Journal:  Circ Arrhythm Electrophysiol       Date:  2011-05-18

8.  Aortic valve sclerosis: is it a cardiovascular risk factor or a cardiac disease marker?

Authors:  Pasquale Palmiero; Maria Maiello; Andrea Passantino; Sanjeev Wasson; Hanumanth K Reddy
Journal:  Echocardiography       Date:  2007-03       Impact factor: 1.724

9.  Epicardial activation of left ventricular wall prolongs QT interval and transmural dispersion of repolarization: implications for biventricular pacing.

Authors:  Jeffrey M Fish; José M Di Diego; Vladislav Nesterenko; Charles Antzelevitch
Journal:  Circulation       Date:  2004-04-12       Impact factor: 29.690

10.  Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample.

Authors:  M Lindroos; M Kupari; J Heikkilä; R Tilvis
Journal:  J Am Coll Cardiol       Date:  1993-04       Impact factor: 24.094

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