Literature DB >> 26063626

Highly sensitive DNA methylation analysis at CpG resolution by surface-enhanced Raman scattering via ligase chain reaction.

Yuling Wang1, Eugene J H Wee, Matt Trau.   

Abstract

Sensitive and accurate DNA methylation analysis at CpG resolution was demonstrated using surface-enhanced Raman scattering (SERS) via ligase chain reaction (LCR). The method was sensitive to 10% changes in methylation and the accuracy of methylation estimates in cells and serum DNA validated with sequencing. The LCR/SERS approach may have broad applications as an alternative (epi)genetic detection method.

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Year:  2015        PMID： 26063626     DOI： 10.1039/c5cc03921e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

Review 1.  Analytical epigenetics: single-molecule optical detection of DNA and histone modifications.

Authors:  Christian Heck; Yael Michaeli; Ilko Bald; Yuval Ebenstein
Journal:  Curr Opin Biotechnol       Date:  2018-10-13       Impact factor: 9.740

2.  Comprehensive evaluation of molecular enhancers of the isothermal exponential amplification reaction.

Authors:  Ellie Mok; Eugene Wee; Yuling Wang; Matt Trau
Journal:  Sci Rep       Date:  2016-12-02       Impact factor: 4.379

3.  Label-free Detection for a DNA Methylation Assay Using Raman Spectroscopy.

Authors:  Jeongho Kim; Hae Jeong Park; Jae Hyung Kim; Boksoon Chang; Hun-Kuk Park
Journal:  Chin Med J (Engl)       Date:  2017-08-20       Impact factor: 2.628

4.  Sensitive detection of methylated DNA and methyltransferase activity based on the lighting up of FAM-labeled DNA quenched fluorescence by gold nanoparticles.

Authors:  Mohammad Ali Karimi; Mehdi Dadmehr; Morteza Hosseini; Behnaz Korouzhdehi; Fatemeh Oroojalian
Journal:  RSC Adv       Date:  2019-04-16       Impact factor: 3.361

Review 5.  Optical bio-sensing of DNA methylation analysis: an overview of recent progress and future prospects.

Authors:  Mina Adampourezare; Mohammad Hasanzadeh; Farzad Seidi
Journal:  RSC Adv       Date:  2022-09-09       Impact factor: 4.036

6.  Simple, Sensitive and Accurate Multiplex Detection of Clinically Important Melanoma DNA Mutations in Circulating Tumour DNA with SERS Nanotags.

Authors:  Eugene J H Wee; Yuling Wang; Simon Chang-Hao Tsao; Matt Trau
Journal:  Theranostics       Date:  2016-06-17       Impact factor: 11.556

Review 7.  Advanced DNA-Based Point-of-Care Diagnostic Methods for Plant Diseases Detection.

Authors:  Han Yih Lau; Jose R Botella
Journal:  Front Plant Sci       Date:  2017-12-06       Impact factor: 5.753

8.  Polymerase chain reaction - surface-enhanced Raman spectroscopy (PCR-SERS) method for gene methylation level detection in plasma.

Authors:  Xiaozhou Li; Tianyue Yang; Caesar Siqi Li; Youtao Song; Deli Wang; Lili Jin; Hong Lou; Wei Li
Journal:  Theranostics       Date:  2020-01-01       Impact factor: 11.556

9.  Multiplex detection of ctDNA mutations in plasma of colorectal cancer patients by PCR/SERS assay.

Authors:  Nana Lyu; Vinoth Kumar Rajendran; Russell J Diefenbach; Kellie Charles; Stephen J Clarke; Alexander Engel; Helen Rizos; Mark P Molloy; Yuling Wang
Journal:  Nanotheranostics       Date:  2020-08-25
  9 in total

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