| Literature DB >> 26062850 |
Xia-Ping He1, Yong-Jin Shu, Jian-Jun Dai, Wen-Man Zhang, Yi-Si Feng, Hua-Jian Xu.
Abstract
A copper-catalysed ring-opening trifluoromethylation reaction of cyclopropanols has been developed. Various β-trifluoromethyl ketones are obtained in good to excellent yields under mild reaction conditions. The present method also exhibits good functional-group compatibility. The mechanism of this new ring-opening trifluoromethylation reaction was investigated by radical trapping reactions.Entities:
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Year: 2015 PMID： 26062850 DOI： 10.1039/c5ob00808e
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876