Literature DB >> 26061508

[The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs].

Isabel Santana1, Filipa Farinha2, Sandra Freitas3, Vítor Rodrigues4, Ålvaro Carvalho5.   

Abstract

INTRODUCTION: The incidence and prevalence of global dementia and Alzheimer's disease (AD) increase with age, almost doubling every five years after the sixth decade of life. Demographic aging is a reality in Portugal, being expectable that the number of dementia cases also increases. Even so, dementia-epidemiological data in Portugal is scarce and cost-of-illness studies are almost inexistent. Our aims were to obtain up-to-date information about the prevalence of dementia/ Alzheimer's disease in Portugal, to estimate the number of cases effectively diagnosed as Alzheimer's disease and to determine illness-costs with specific dementia treatment.
MATERIAL AND METHODS: The numbers of age-adjusted prevalence of dementia obtained for Occidental Europe (Alzheimer's Disease International study), where applied to the resident population in Portugal (2013). Estimations related to diagnosis and treatment-costs were based in data provided by the Intercontinental Marketing Services Health (IMSH)-2013.
RESULTS: The estimated number of Portuguese people with dementia among those aged ≥60 years, is 160,287, representing 5.91% of this population-stratum. Knowing Alzheimer's disease is responsible for 50-70% of all cases, we might conclude there are between 80,144 and 112,201 patients. According to IMSH-data, 76250 receive anti-dementia drugs and the costs of this kind of medication is 37 M€¬/year.
CONCLUSIONS: As a consequence of the demographic aging, also the number of dementia cases increases. Apparently, not all Alzheimer's disease patients receive the recommended medication, suggesting this condition is still under-diagnosed. However, figures indicate a positive progression with an increment of treated cases and a reduction of medication-costs.

Entities:  

Mesh:

Year:  2015        PMID: 26061508

Source DB:  PubMed          Journal:  Acta Med Port        ISSN: 0870-399X


  10 in total

Review 1.  The Government's role in regulating, coordinating, and standardizing the response to Alzheimer's disease: Anticipated international cooperation in the area of intractable and rare diseases.

Authors:  Qi Tang; Peipei Song; Lingzhong Xu
Journal:  Intractable Rare Dis Res       Date:  2016-11

Review 2.  Emerging Roles of Sirtuin 6 in Alzheimer's Disease.

Authors:  Nurul Fatihah Mohamad Nasir; Azalina Zainuddin; Shaharum Shamsuddin
Journal:  J Mol Neurosci       Date:  2017-12-19       Impact factor: 3.444

3.  Protective effect of tetrahydroxy stilbene glucoside on learning and memory by regulating synaptic plasticity.

Authors:  Hong-Bo Luo; Yun Li; Zun-Jing Liu; Li Cao; Zhi-Qiang Zhang; Yong Wang; Xiao-Yan Zhang; Zhao Liu; Xiang-Qun Shi
Journal:  Neural Regen Res       Date:  2016-09       Impact factor: 5.135

4.  Screening of Dementia in Portuguese Primary Care: Methodology, Assessment Tools, and Main Results.

Authors:  Laetitia Teixeira; Pedro Machado Dos Santos; Sara Alves; Maria João Azevedo; Mafalda Gomes Duarte; António Leuschner; Constança Paúl
Journal:  Front Med (Lausanne)       Date:  2017-11-13

5.  Mild Cognitive Impairment with a High Risk of Progression to Alzheimer's Disease Dementia (MCI-HR-AD): Effect of Souvenaid® Treatment on Cognition and 18F-FDG PET Scans.

Authors:  Maria Sagrario Manzano Palomo; Belen Anaya Caravaca; Maria Angeles Balsa Bretón; Sergio Muñiz Castrillo; Asuncion de la Morena Vicente; Eduardo Castro Arce; María Teresa Alves Prez
Journal:  J Alzheimers Dis Rep       Date:  2019-05-03

6.  Combined Modeling Study of the Binding Characteristics of Natural Compounds, Derived from Psoralea Fruits, to β-Amyloid Peptide Monomer.

Authors:  Awwad Radwan; Fars Alanazi
Journal:  Int J Mol Sci       Date:  2022-03-24       Impact factor: 5.923

Review 7.  Current Research Therapeutic Strategies for Alzheimer's Disease Treatment.

Authors:  Jaume Folch; Dmitry Petrov; Miren Ettcheto; Sonia Abad; Elena Sánchez-López; M Luisa García; Jordi Olloquequi; Carlos Beas-Zarate; Carme Auladell; Antoni Camins
Journal:  Neural Plast       Date:  2016-01-03       Impact factor: 3.599

8.  The prevalence of dementia in a Portuguese community sample: a 10/66 Dementia Research Group study.

Authors:  Manuel Gonçalves-Pereira; Ana Cardoso; Ana Verdelho; Joaquim Alves da Silva; Manuel Caldas de Almeida; Alexandra Fernandes; Cátia Raminhos; Cleusa P Ferri; A Matthew Prina; Martin Prince; Miguel Xavier
Journal:  BMC Geriatr       Date:  2017-11-07       Impact factor: 3.921

Review 9.  A Review on Tramiprosate (Homotaurine) in Alzheimer's Disease and Other Neurocognitive Disorders.

Authors:  Sagrario Manzano; Luis Agüera; Miquel Aguilar; Javier Olazarán
Journal:  Front Neurol       Date:  2020-07-07       Impact factor: 4.003

Review 10.  Current Understanding of the Physiopathology, Diagnosis and Therapeutic Approach to Alzheimer's Disease.

Authors:  Victoria García-Morales; Anabel González-Acedo; Lucía Melguizo-Rodríguez; Teresa Pardo-Moreno; Víctor Javier Costela-Ruiz; María Montiel-Troya; Juan José Ramos-Rodríguez
Journal:  Biomedicines       Date:  2021-12-14
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.