Literature DB >> 26061479

A Fluorescent Sensor and Gel Stain for Detection of Pyrophosphorylated Proteins.

Florence J Williams1, Dorothea Fiedler1.   

Abstract

The design and synthesis of a fluorescent sensor of diphosphate esters along with its application for in-gel detection is described. Dinuclear zinc complex 1 selectively binds diphosphate esters in the presence of various other functional groups, including monophosphate esters. Complex 1 also constitutes a competent stain for visualization of pyrophosphorylated proteins in polyacrylamide gels. This reagent will facilitate the validation and exploration of protein pyrophosphorylation.

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Year:  2015        PMID： 26061479     DOI： 10.1021/acschembio.5b00256

Source DB:  PubMed          Journal:  ACS Chem Biol        ISSN： 1554-8929            Impact factor:   5.100


  6 in total

Review 1.  Imaging and therapeutic applications of zinc(ii)-dipicolylamine molecular probes for anionic biomembranes.

Authors:  Douglas R Rice; Kasey J Clear; Bradley D Smith
Journal:  Chem Commun (Camb)       Date:  2016-07-07       Impact factor: 6.222

Review 2.  The inositol pyrophosphate pathway in health and diseases.

Authors:  Anutosh Chakraborty
Journal:  Biol Rev Camb Philos Soc       Date:  2017-12-27

Review 3.  Intimate connections: Inositol pyrophosphates at the interface of metabolic regulation and cell signaling.

Authors:  Stephen B Shears
Journal:  J Cell Physiol       Date:  2017-06-15       Impact factor: 6.384

4.  Label-Free Direct Electrical Detection of a Histidine-Rich Protein with Sub-Femtomolar Sensitivity using an Organic Field-Effect Transistor.

Authors:  Tsukuru Minamiki; Yui Sasaki; Shizuo Tokito; Tsuyoshi Minami
Journal:  ChemistryOpen       Date:  2017-06-12       Impact factor: 2.911

5.  Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport.

Authors:  Manasa Chanduri; Ashim Rai; Aushaq Bashir Malla; Mingxuan Wu; Dorothea Fiedler; Roop Mallik; Rashna Bhandari
Journal:  Biochem J       Date:  2016-07-29       Impact factor: 3.857

Review 6.  Identity and functions of inorganic and inositol polyphosphates in plants.

Authors:  Laura Lorenzo-Orts; Daniel Couto; Michael Hothorn
Journal:  New Phytol       Date:  2019-09-20       Impact factor: 10.151
  6 in total

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