| Literature DB >> 26057289 |
Caroline M P G van Durme1, Mihir D Wechalekar2, Robert B M Landewé3.
Abstract
CLINICAL QUESTION: Are nonsteroidal anti-inflammatory drugs (NSAIDs) associated with better outcomes than cyclooxygenase inhibitors, glucocorticoids, IL-1 inhibitors or placebo in the treatment of acute gout? BOTTOM LINE: NSAIDs are not significantly associated with a difference in pain reduction compared with cyclooxygenase inhibitors and glucocorticoids for treating acute gout. However, NSAIDs are associated with higher rates of adverse events and higher rates of withdrawal due to adverse events compared with cyclooxygenase inhibitors.Entities:
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Year: 2015 PMID： 26057289 DOI： 10.1001/jama.2015.1881
Source DB: PubMed Journal: JAMA ISSN： 0098-7484 Impact factor: 56.272