| Literature DB >> 26055967 |
Takahiro Fukuhara1, Eriko Matsuda2, Yukari Endo3, Masao Takenobu2, Shoichiro Izawa4, Kazunori Fujiwara2, Hiroya Kitano2.
Abstract
The aim of this study was to determine the correlation between shear wave velocity (SWV) generated by acoustic radiation force impulse and the pathologic structure of thyroid lesions. A total of 599 thyroid tissue samples were divided into four groups based on pathologic structure: 254 normal thyroid tissue samples as a control, 128 with chronic autoimmune thyroiditis (CAT) that demonstrated diffuse fibrosis, 165 with benign nodules that had high cell density and 52 with papillary thyroid carcinoma (PTC) that showed high cell density and fibrosis. The mean SWVs in each group were as follows: 1.60 ± 0.18 m/s in normal thyroid, 2.55 ± 0.28 m/s in CAT, 1.72 ± 0.31 m/s in benign nodules and 2.66 ± 0.95 m/s in PTC. The SWVs of CAT and PTC were significantly higher than those of normal thyroid, (p < 0.001). SWV was significantly affected by fibrosis.Entities:
Keywords: Acoustic radiation force impulse; Chronic autoimmune thyroiditis; Fibrosis; Papillary thyroid carcinoma; Pathologic structure; Shear wave; Thyroid
Mesh：
Year: 2015 PMID： 26055967 DOI： 10.1016/j.ultrasmedbio.2015.05.001
Source DB: PubMed Journal: Ultrasound Med Biol ISSN： 0301-5629 Impact factor: 2.998