Literature DB >> 2605504

Monoclonal antibodies to study the brain in schizophrenia.

W G Honer1, C A Kaufmann, J E Kleinman, M F Casanova, P Davies.   

Abstract

Twelve monoclonal antibodies were developed which show selective reactivity with brain tissue homogenates from 4 patients with schizophrenia compared to 4 normal controls. Certain antibodies were more reactive with tissue from cases with schizophrenia, others with control tissue. Patterns of reactivity also depended on brain region tested. Differences in reactivity generally ranged from 2- to as much as 8-fold. This panel of monoclonal antibodies may be useful to investigate the pathophysiology of schizophrenia.

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Year:  1989        PMID: 2605504     DOI: 10.1016/0006-8993(89)90335-1

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  6 in total

Review 1.  Assessing the machinery of mind: synapses in neuropsychiatric disorders.

Authors:  W G Honer
Journal:  J Psychiatry Neurosci       Date:  1999-03       Impact factor: 6.186

2.  Staging of cytoskeletal and beta-amyloid changes in human isocortex reveals biphasic synaptic protein response during progression of Alzheimer's disease.

Authors:  E B Mukaetova-Ladinska; F Garcia-Siera; J Hurt; H J Gertz; J H Xuereb; R Hills; C Brayne; F A Huppert; E S Paykel; M McGee; R Jakes; W G Honer; C R Harrington; C M Wischik
Journal:  Am J Pathol       Date:  2000-08       Impact factor: 4.307

3.  Two RFLPs near HOX2@/NGFR at locus D17S444E.

Authors:  J L Kennedy; W G Honer; C A Kaufmann; J A Martignetti; J Brosius; K K Kidd
Journal:  Nucleic Acids Res       Date:  1992-03-11       Impact factor: 16.971

4.  A genotype-phenotype research strategy for schizophrenia.

Authors:  W G Honer; A S Bassett; L Kopala; J L Kennedy
Journal:  Can J Psychiatry       Date:  1990-12       Impact factor: 4.356

5.  Late-life physical activity relates to brain tissue synaptic integrity markers in older adults.

Authors:  Kaitlin Casaletto; Alfredo Ramos-Miguel; Anna VandeBunte; Molly Memel; Aron Buchman; David Bennett; William Honer
Journal:  Alzheimers Dement       Date:  2022-01-07       Impact factor: 16.655

6.  Microglial Correlates of Late Life Physical Activity: Relationship with Synaptic and Cognitive Aging in Older Adults.

Authors:  Kaitlin B Casaletto; Cutter A Lindbergh; Anna VandeBunte; John Neuhaus; Julie A Schneider; Aron S Buchman; William G Honer; David A Bennett
Journal:  J Neurosci       Date:  2021-11-22       Impact factor: 6.709

  6 in total

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