Literature DB >> 26055027

Treatment of Tendon Injuries of the Lower Limb with Growth Factors Associated with Autologous Fibrin Scaffold or Collagenous Scaffold.

Stefano Giannotti1, Giacomo Dell'Osso1, Vanna Bottai1, Marco Ghilardi1, Giulia Bugelli1, Ilaria Lazzerini1, Giulio Guido1.   

Abstract

Tendon injuries are an increasing problem in orthopedics as we are faced with a growing demand in sports and recreation and an aging population. Tendons have poor spontaneous regenerative capacity, and often, complete recovery after injury is not achieved. Once injured, tendons do not completely re-acquire the biological and biomechanical properties of normal tendons due to the formation of adhesions and scarring, and often these abnormalities in the arrangement and structure are risk factors for re-injury. These problems associated with the healing of tendon injuries are a challenge for clinicians and surgeons. This study examined 9 cases of subcutaneous injuries including quadriceps tendon (2 cases), patellar tendon (1 case), and Achilles tendon (6 cases), incomplete and complete, treated consecutively. The surgical technique has provided, as appropriate, the termino-terminal tenorraphy, techniques of plastics of rotation flap, reinsertion with suture anchors, and in one case tendon augmentation with cadaver tissue. In cases where we needed mechanical support to the suture, we used preloaded growth factors on porcine collagen scaffold; in cases where we needed only one biological support, we used fibrin scaffold.

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Year:  2015        PMID: 26055027

Source DB:  PubMed          Journal:  Surg Technol Int        ISSN: 1090-3941


  2 in total

Review 1.  Feasibility of Growth Factor Agent Therapy in Repairing Motor Injury.

Authors:  Qiaoyin Tan; Jiayu Li; Yuwen Liu; Xiaojuan Zhu; Weide Shao
Journal:  Front Pharmacol       Date:  2022-01-25       Impact factor: 5.810

2.  Extracellular matrix supports healing of transected rabbit Achilles tendon.

Authors:  Marija Lipar; Boris Zdilar; Mario Kreszinger; Marijana Ćorić; Berislav Radišić; Marko Samardžija; Rado Žic; Marko Pećin
Journal:  Heliyon       Date:  2018-09-10
  2 in total

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