Literature DB >> 26054449

Successful treatment with infliximab for refractory para-ileostomal ulceration in a patient with Behҫet's disease.

Mitsuaki Ishioka1, Kengo Onochi, Yusato Suzuki, Masayuki Sawaguchi, Natsumi Hatakeyama, Shigeto Koizumi, Tamotsu Matsuhashi, Mario Jin, Hirohide Ohnishi.   

Abstract

Behҫet's disease (BD) is a chronic disorder involving multiple organ systems including the small and large intestines. A 46-year-old female diagnosed with intestinal BD presented with ileocecal perforation and diffuse peritonitis and subsequently underwent ileocolic resection with ileostomy. After surgery, she suffered from refractory para-ileostomal ulceration associated with BD. Most importantly, however, treatment with infliximab was significantly effective in healing the ulceration. This is the first report of para-ileostomal ulceration associated with BD successfully treated with infliximab, suggesting the possible use of infliximab as a therapeutic option for para-stomal ulcers related to BD.

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Year:  2015        PMID: 26054449     DOI: 10.1007/s12328-015-0576-9

Source DB:  PubMed          Journal:  Clin J Gastroenterol        ISSN: 1865-7265


  12 in total

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4.  Prognostic factors and long-term clinical outcomes for surgical patients with intestinal Behcet's disease.

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Journal:  Inflamm Bowel Dis       Date:  2010-11-08       Impact factor: 5.325

Review 5.  Behçet's syndrome: a critical digest of the 2013-2014 literature.

Authors:  Gulen Hatemi; Emire Seyahi; Izzet Fresko; Rosaria Talarico; Vedat Hamuryudan
Journal:  Clin Exp Rheumatol       Date:  2014-09-30       Impact factor: 4.473

6.  Topical negative pressure therapy for para-ileostomal ulceration in a patient with Behçet's disease.

Authors:  N Ohura; M Okazaki; M Tanba; M Kinoshita; A Takushima; K Harii
Journal:  J Wound Care       Date:  2008-02       Impact factor: 2.072

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Authors:  Haruko Ideguchi; Akiko Suda; Mitsuhiro Takeno; Rumiko Miyagi; Atsuhisa Ueda; Shigeru Ohno; Yoshiaki Ishigatsubo
Journal:  Rheumatol Int       Date:  2013-08-10       Impact factor: 2.631

8.  Efficacy of infliximab for induction and maintenance of remission in intestinal Behçet's disease.

Authors:  Makoto Naganuma; Atsushi Sakuraba; Tadakazu Hisamatsu; Hiroki Ochiai; Hirotoshi Hasegawa; Haruhiko Ogata; Yasushi Iwao; Toshifumi Hibi
Journal:  Inflamm Bowel Dis       Date:  2008-09       Impact factor: 5.325

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Journal:  Mediators Inflamm       Date:  2013-08-01       Impact factor: 4.711

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  2 in total

Review 1.  Updated treatment strategies for intestinal Behçet's disease.

Authors:  Yong Eun Park; Jae Hee Cheon
Journal:  Korean J Intern Med       Date:  2017-12-08       Impact factor: 2.884

2.  Successful closure of ileostomy in a patient with intestinal Behçet's disease after therapy with adalimumab: A case report.

Authors:  Zhe Yan; Bei-Bei Cui; Yong-Yang Yu; Geng Yin; Xiao-Min Cen; Qi-Bing Xie
Journal:  Medicine (Baltimore)       Date:  2019-03       Impact factor: 1.889

  2 in total

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