Luke R Putnam1, Courtney M Chang2, Nathan B Rogers2, Jason M Podolnick2, Shruti Sakhuja2, Maria Matusczcak3, Mary T Austin1, Lillian S Kao4, Kevin P Lally1, KuoJen Tsao5. 1. Center for Surgical Trials and Evidence-based Practice, Houston, TX; Department of Pediatric Surgery, University of Texas Medical School at Houston, Houston, TX; The Children's Memorial Hermann Hospital, Houston, TX. 2. Center for Surgical Trials and Evidence-based Practice, Houston, TX; Department of Pediatric Surgery, University of Texas Medical School at Houston, Houston, TX. 3. Department of Pediatric Surgery, University of Texas Medical School at Houston, Houston, TX; The Children's Memorial Hermann Hospital, Houston, TX. 4. Center for Surgical Trials and Evidence-based Practice, Houston, TX; Department of Surgery, University of Texas Medical School at Houston, Houston, TX. 5. Center for Surgical Trials and Evidence-based Practice, Houston, TX; Department of Pediatric Surgery, University of Texas Medical School at Houston, Houston, TX; The Children's Memorial Hermann Hospital, Houston, TX. Electronic address: Kuojen.Tsao@uth.tmc.edu.
Abstract
BACKGROUND: Adherence to prophylactic antibiotics guidelines is challenging and poorly documented. We hypothesized that a multiphase, multifaceted quality improvement initiative would engage relevant stakeholders, address known barriers to adoption, and improve overall adherence. METHODS: From 2011 to 2014, a series of interventions were introduced in the pediatric operating rooms. After each interventional period, prospective assessments were performed to record the antibiotic type, dose, timing, and redosing according to the guidelines. Perioperative factors that may influence guideline adherence were analyzed. Spearman's rank correlation, analysis of variance, and χ(2) tests were performed. RESULTS: A total of 1,052 operations were observed, and 629 (60%) required prophylactic antibiotics. Adherence to all 4 guideline components remained unchanged (54-55%, P = .38). Redosing significantly improved (7-53%, P = .02), but correct type decreased (98-70%, P < .01). The percentage of cases in which only one antibiotic guideline component was missed remained unchanged (35-34%, P = .46). Adherence to guidelines was not significantly associated with American Society of Anesthesiologists class, surgical specialty, patient weight, anesthesia provider, or surgical wound class. CONCLUSION: Despite multiple interventions to improve antibiotic prophylaxis, overall adherence did not improve. Most interventions were directed at the point of administration in the operating room; future implementation strategies should focus on the perioperative setting.
BACKGROUND: Adherence to prophylactic antibiotics guidelines is challenging and poorly documented. We hypothesized that a multiphase, multifaceted quality improvement initiative would engage relevant stakeholders, address known barriers to adoption, and improve overall adherence. METHODS: From 2011 to 2014, a series of interventions were introduced in the pediatric operating rooms. After each interventional period, prospective assessments were performed to record the antibiotic type, dose, timing, and redosing according to the guidelines. Perioperative factors that may influence guideline adherence were analyzed. Spearman's rank correlation, analysis of variance, and χ(2) tests were performed. RESULTS: A total of 1,052 operations were observed, and 629 (60%) required prophylactic antibiotics. Adherence to all 4 guideline components remained unchanged (54-55%, P = .38). Redosing significantly improved (7-53%, P = .02), but correct type decreased (98-70%, P < .01). The percentage of cases in which only one antibiotic guideline component was missed remained unchanged (35-34%, P = .46). Adherence to guidelines was not significantly associated with American Society of Anesthesiologists class, surgical specialty, patient weight, anesthesia provider, or surgical wound class. CONCLUSION: Despite multiple interventions to improve antibiotic prophylaxis, overall adherence did not improve. Most interventions were directed at the point of administration in the operating room; future implementation strategies should focus on the perioperative setting.
Authors: Daniela Bertschi; Walter P Weber; Jasmin Zeindler; Daniel Stekhoven; Robert Mechera; Lilian Salm; Marco Kralijevic; Savas D Soysal; Marco von Strauss; Edin Mujagic; Walter R Marti Journal: World J Surg Date: 2019-10 Impact factor: 3.352
Authors: Rabie Kilan; Dane Moran; Iyad Eid; Christopher Okeahialam; Corrine Quinn; Wadie Binsaddiq; Tammy Williams; Michael H Johnson Journal: Ann Med Surg (Lond) Date: 2017-06-15
Authors: D Donà; E Barbieri; M Daverio; R Lundin; C Giaquinto; T Zaoutis; M Sharland Journal: Antimicrob Resist Infect Control Date: 2020-01-03 Impact factor: 4.887