Literature DB >> 26053709

Monitoring the Effect of Immunotherapy in Autoimmune Limbic Encephalitis Using 18F-FDG PET.

Cristina Trevino-Peinado1, Javier Arbizu, Pablo Irimia, Mario Riverol, Eduardo Martínez-Vila.   

Abstract

A 70-year-old woman with a history of autoimmune hepatitis and renal cell carcinoma presented with subacute cognitive impairment. A brain MRI revealed mild leukoaraiosis, whereas brain F-FDG PET/CT showed diffuse cerebral hypometabolism that resembled some of the patterns described in limbic encephalitis and neurodegenerative diseases. With the suspicion of autoimmune encephalitis, the patient received immunotherapy with dramatic improvement of cognitive function and metabolic normalization at the 2-month follow-up on brain F-FDG PET/CT. Our results demonstrate that brain F-FDG PET/CT might be a useful tool in the assessment of patients with autoimmune encephalitis.

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Year:  2015        PMID: 26053709     DOI: 10.1097/RLU.0000000000000839

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN: 0363-9762            Impact factor:   7.794


  3 in total

1.  The need of standardization and of large clinical studies in an emerging indication of [18F]FDG PET: the autoimmune encephalitis.

Authors:  Silvia Morbelli; Javier Arbizu; Jan Booij; Ming-Kai Chen; Gael Chetelat; Donna J Cross; Mehdi Djekidel; Alexander Drzezga; Ozgul Ekmekcioglu; Valentina Garibotto; Swen Hesse; Kazunari Ishii; Lida Jafari; Adriaan A Lammertsma; Ian Law; Dana Mathews; Satoshi Minoshima; Karina Mosci; Marco Pagani; Sabina Pappata; Daniel Hillel Silverman; Alberto Signore; Elsmarieke Van De Giessen; Victor Villemagne; Henryk Barthel
Journal:  Eur J Nucl Med Mol Imaging       Date:  2016-12-06       Impact factor: 9.236

Review 2.  Life after autoantibody-mediated encephalitis: optimizing follow-up and management in recovering patients.

Authors:  Pierpaolo Turcano; Gregory S Day
Journal:  Curr Opin Neurol       Date:  2022-06-01       Impact factor: 6.283

3.  Lewy Body Dementia Associated with Anti-IgLON 5 Encephalitis Detected on 18F Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and 99mTc-TRODAT Single-Photon Emission Computed Tomography/Computed Tomography.

Authors:  Nikhil Seniaray; Ritu Verma; Rajeev Ranjan; Ethel Belho; Harsh Mahajan
Journal:  Indian J Nucl Med       Date:  2022-03-25
  3 in total

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