| Literature DB >> 26053358 |
Ben Niu1, Wannian Zhao1, Yingcai Ding1, Zhaogang Bian1, Charles U Pittman2, Aihua Zhou1, Haibo Ge3.
Abstract
Coumarin and flavone derivatives are highly valuable molecules in drug discovery. Here, two new regioselective cross-dehydrogenation couplings of coumarins and flavones with different ethers via C(sp(3))-H functionalization processes were developed, generating new ether-substituted derivatives not previously reported. These reactions proceeded well via radical mechanisms and provided the corresponding products in good yields.Entities:
Mesh：
Substances：
Year: 2015 PMID： 26053358 DOI： 10.1021/acs.joc.5b00800
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354