Christina Brei1, Daniela Much1, Ellen Heimberg2, Verena Schulte1, Stefanie Brunner1, Lynne Stecher1, Christiane Vollhardt1, Jan S Bauer3, Ulrike Amann-Gassner1, Hans Hauner4. 1. Else Kröner-Fresenius-Center for Nutritional Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany. 2. Department of Pediatrics, Universitätsklinikum Tübingen, Tübingen, Germany. 3. Department of Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany. 4. 1] Else Kröner-Fresenius-Center for Nutritional Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany [2] ZIEL - Research Center for Nutrition and Food Science, Nutritional Medicine Unit, Technische Universität and München, Freising, Germany.
Abstract
BACKGROUND: Longitudinal data regarding the fat distribution in the early postnatal period is sparse. METHODS: We performed ultrasonography (US) as a noninvasive approach to investigate the development of abdominal subcutaneous (SC) and preperitoneal (PP) fat depots in infants ≤1 y and compared longitudinal US data with skinfold thickness (SFT) measurements and anthropometry in 162 healthy children at 6 wk, 4 mo, and 1 y postpartum. RESULTS: US was found to be a reproducible method for the quantification of abdominal SC and PP adipose tissue (AT) in this age group. Thickness of SC fat layers significantly increased from 6 wk to 4 mo and decreased at 1 y postpartum, whereas PP fat layers continuously increased. Girls had a significantly higher SC fat mass compared to boys, while there was no sex-specific difference in PP fat thickness. SC fat layer was strongly correlated with SFT measurements, while PP fat tissue was only weakly correlated with anthropometric measures. CONCLUSION: US is a feasible and reproducible method for the quantification of abdominal fat mass in infants ≤1 y of age. PP and SC fat depots develop differentially during the first year of life.
RCT Entities:
BACKGROUND: Longitudinal data regarding the fat distribution in the early postnatal period is sparse. METHODS: We performed ultrasonography (US) as a noninvasive approach to investigate the development of abdominal subcutaneous (SC) and preperitoneal (PP) fat depots in infants ≤1 y and compared longitudinal US data with skinfold thickness (SFT) measurements and anthropometry in 162 healthy children at 6 wk, 4 mo, and 1 y postpartum. RESULTS: US was found to be a reproducible method for the quantification of abdominal SC and PP adipose tissue (AT) in this age group. Thickness of SC fat layers significantly increased from 6 wk to 4 mo and decreased at 1 y postpartum, whereas PP fat layers continuously increased. Girls had a significantly higher SC fat mass compared to boys, while there was no sex-specific difference in PP fat thickness. SC fat layer was strongly correlated with SFT measurements, while PP fat tissue was only weakly correlated with anthropometric measures. CONCLUSION: US is a feasible and reproducible method for the quantification of abdominal fat mass in infants ≤1 y of age. PP and SC fat depots develop differentially during the first year of life.
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