| Literature DB >> 26052800 |
Mikako Kawashima1, Taro Usui1, Hideyuki Okada1, Ichiro Mori1, Masahiro Yamauchi1, Takahide Ikeda1, Kazuo Kajita1, Yusuke Kito2, Tatsuhiko Miyazaki2, Kei Fujioka3, Tatsuo Ishizuka3, Hiroyuki Morita1.
Abstract
Recently, more than ten cases of thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly (TAFRO) syndrome or Castleman-Kojima disease exhibiting such symptoms as thrombocytopenia, anasarca, fever, reticulin fibrosis and organomegaly have been reported in Japan. We have found two cases of TAFRO syndrome and have reviewed another eighteen previously reported cases. Histological findings of the lymph nodes and levels of interleukin 6 (IL-6) and vascular endothelial growth factor in both serum/plasma and effusions are important characteristics for diagnosing this syndrome.Entities:
Keywords: Anasarca; Fever; Organomegaly; Reticulin fibrosis; Thrombocytopenia
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Year: 2015 PMID: 26052800 DOI: 10.3109/14397595.2015.1059982
Source DB: PubMed Journal: Mod Rheumatol ISSN: 1439-7595 Impact factor: 3.023