Literature DB >> 26052661

Bottlenecks in HIV-1 transmission: insights from the study of founder viruses.

Sarah B Joseph1, Ronald Swanstrom2, Angela D M Kashuba3, Myron S Cohen4.   

Abstract

HIV-1 infection typically results from the transmission of a single viral variant, the transmitted/founder (T/F) virus. Studies of these HIV-1 variants provide critical information about the transmission bottlenecks and the selective pressures acting on the virus in the transmission fluid and in the recipient tissues. These studies reveal that T/F virus phenotypes are shaped by stochastic and selective forces that restrict transmission and may be targets for prevention strategies. In this Review, we highlight how studies of T/F viruses contribute to a better understanding of the biology of HIV-1 transmission and discuss how these findings affect HIV-1 prevention strategies.

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Year:  2015        PMID： 26052661      PMCID： PMC4793885          DOI： 10.1038/nrmicro3471

Source DB:  PubMed          Journal:  Nat Rev Microbiol        ISSN： 1740-1526            Impact factor:   60.633


  121 in total

1.  Decrease in human immunodeficiency virus type 1 load during acute dengue fever.

Authors:  George Watt; Pacharee Kantipong; Krisada Jongsakul
Journal:  Clin Infect Dis       Date:  2003-04-04       Impact factor: 9.079

2.  Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group.

Authors:  T C Quinn; M J Wawer; N Sewankambo; D Serwadda; C Li; F Wabwire-Mangen; M O Meehan; T Lutalo; R H Gray
Journal:  N Engl J Med       Date:  2000-03-30       Impact factor: 91.245

3.  Acute sexually transmitted infections increase human immunodeficiency virus type 1 plasma viremia, increase plasma type 2 cytokines, and decrease CD4 cell counts.

Authors:  A O Anzala; J N Simonsen; J Kimani; T B Ball; N J Nagelkerke; J Rutherford; E N Ngugi; J J Bwayo; F A Plummer
Journal:  J Infect Dis       Date:  2000-07-12       Impact factor: 5.226

4.  Human immunodeficiency virus type 1 shedding pattern in semen correlates with the compartmentalization of viral Quasi species between blood and semen.

Authors:  P Gupta; C Leroux; B K Patterson; L Kingsley; C Rinaldo; M Ding; Y Chen; K Kulka; W Buchanan; B McKeon; R Montelaro
Journal:  J Infect Dis       Date:  2000-06-29       Impact factor: 5.226

5.  Suppression of human immunodeficiency virus replication during acute measles.

Authors:  William J Moss; Judith J Ryon; Mwaka Monze; Felicity Cutts; Thomas C Quinn; Diane E Griffin
Journal:  J Infect Dis       Date:  2002-03-25       Impact factor: 5.226

6.  Antibody neutralization and escape by HIV-1.

Authors:  Xiping Wei; Julie M Decker; Shuyi Wang; Huxiong Hui; John C Kappes; Xiaoyun Wu; Jesus F Salazar-Gonzalez; Maria G Salazar; J Michael Kilby; Michael S Saag; Natalia L Komarova; Martin A Nowak; Beatrice H Hahn; Peter D Kwong; George M Shaw
Journal:  Nature       Date:  2003-03-20       Impact factor: 49.962

7.  HLA allele sharing and HIV type 1 viremia in seroconverting Zambians with known transmitting partners.

Authors:  Jianming Tang; Shenghui Tang; Elena Lobashevsky; Isaac Zulu; Grace Aldrovandi; Susan Allen; Richard A Kaslow
Journal:  AIDS Res Hum Retroviruses       Date:  2004-01       Impact factor: 2.205

8.  HIV evolution: CTL escape mutation and reversion after transmission.

Authors:  A J Leslie; K J Pfafferott; P Chetty; R Draenert; M M Addo; M Feeney; Y Tang; E C Holmes; T Allen; J G Prado; M Altfeld; C Brander; C Dixon; D Ramduth; P Jeena; S A Thomas; A St John; T A Roach; B Kupfer; G Luzzi; A Edwards; G Taylor; H Lyall; G Tudor-Williams; V Novelli; J Martinez-Picado; P Kiepiela; B D Walker; P J R Goulder
Journal:  Nat Med       Date:  2004-02-08       Impact factor: 53.440

9.  Candidate microbicides block HIV-1 infection of human immature Langerhans cells within epithelial tissue explants.

Authors:  T Kawamura; S S Cohen; D L Borris; E A Aquilino; S Glushakova; L B Margolis; J M Orenstein; R E Offord; A R Neurath; A Blauvelt
Journal:  J Exp Med       Date:  2000-11-20       Impact factor: 14.307

10.  R5 HIV productively infects Langerhans cells, and infection levels are regulated by compound CCR5 polymorphisms.

Authors:  Tatsuyoshi Kawamura; Forrest O Gulden; Makoto Sugaya; David T McNamara; Debra L Borris; Michael M Lederman; Jan M Orenstein; Peter A Zimmerman; Andrew Blauvelt
Journal:  Proc Natl Acad Sci U S A       Date:  2003-06-18       Impact factor: 12.779
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  86 in total

1.  Comparison of cluster-based and source-attribution methods for estimating transmission risk using large HIV sequence databases.

Authors:  Stéphane Le Vu; Oliver Ratmann; Valerie Delpech; Alison E Brown; O Noel Gill; Anna Tostevin; Christophe Fraser; Erik M Volz
Journal:  Epidemics       Date:  2017-10-20       Impact factor: 4.396

Review 2.  Heterogeneity in tuberculosis.

Authors:  Anthony M Cadena; Sarah M Fortune; JoAnne L Flynn
Journal:  Nat Rev Immunol       Date:  2017-07-24       Impact factor: 53.106

3.  Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells.

Authors:  Guinevere Q Lee; Nina Orlova-Fink; Kevin Einkauf; Fatema Z Chowdhury; Xiaoming Sun; Sean Harrington; Hsiao-Hsuan Kuo; Stephane Hua; Hsiao-Rong Chen; Zhengyu Ouyang; Kavidha Reddy; Krista Dong; Thumbi Ndung'u; Bruce D Walker; Eric S Rosenberg; Xu G Yu; Mathias Lichterfeld
Journal:  J Clin Invest       Date:  2017-06-19       Impact factor: 14.808

4.  Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral infectivity.

Authors:  Ujjwal Rathore; Piyali Saha; Sannula Kesavardhana; Aditya Arun Kumar; Rohini Datta; Sivasankar Devanarayanan; Raksha Das; John R Mascola; Raghavan Varadarajan
Journal:  J Biol Chem       Date:  2017-04-26       Impact factor: 5.157

5.  Mutations present in a low-passage Zika virus isolate result in attenuated pathogenesis in mice.

Authors:  Nisha K Duggal; Erin M McDonald; James Weger-Lucarelli; Seth A Hawks; Jana M Ritter; Hannah Romo; Gregory D Ebel; Aaron C Brault
Journal:  Virology       Date:  2019-02-07       Impact factor: 3.616

Review 6.  What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans? Rigorous Simian Immunodeficiency Virus Vaccine Trials Can Be Instructive.

Authors:  Mauricio A Martins; David I Watkins
Journal:  Cold Spring Harb Perspect Biol       Date:  2018-04-02       Impact factor: 10.005

7.  Evidence for both Intermittent and Persistent Compartmentalization of HIV-1 in the Female Genital Tract.

Authors:  Batsirai M Mabvakure; Bronwen E Lambson; Kavisha Ramdayal; Lindi Masson; Dale Kitchin; Mushal Allam; Salim Abdool Karim; Carolyn Williamson; Jo-Ann Passmore; Darren P Martin; Cathrine Scheepers; Penny L Moore; Gordon W Harkins; Lynn Morris
Journal:  J Virol       Date:  2019-05-01       Impact factor: 5.103

Review 8.  Complex immune correlates of protection in HIV-1 vaccine efficacy trials.

Authors:  Georgia D Tomaras; Stanley A Plotkin
Journal:  Immunol Rev       Date:  2017-01       Impact factor: 12.988

9.  Transmitted/Founder HIV-1 Subtype C Viruses Show Distinctive Signature Patterns in Vif, Vpr, and Vpu That Are Under Subsequent Immune Pressure During Early Infection.

Authors:  Raabya Rossenkhan; Iain J MacLeod; Zabrina L Brumme; Craig A Magaret; Theresa K Sebunya; Rosemary Musonda; Berhanu A Gashe; Paul T Edlefsen; Vlad Novitsky; M Essex
Journal:  AIDS Res Hum Retroviruses       Date:  2016-07-26       Impact factor: 2.205

10.  Interferon-I: The Pièce de Résistance of HIV-1 Transmission?

Authors:  Damien C Tully; Daniel T Claiborne; Todd M Allen
Journal:  Trends Microbiol       Date:  2017-03-09       Impact factor: 17.079
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