| Literature DB >> 26052050 |
Giandomenico Roviello1, Roberto Petrioli2, Letizia Laera2, Edoardo Francini3.
Abstract
New agents for metastatic castration-resistant prostate cancer (CRPC) developed in the past 3 years include cabaziataxel (Cbz), abiraterone acetate (AA) and enzalutamide (E). In this review, the results of clinical studies in which one of these drugs is included as the third line of treatment are discussed. Our review suggests that AA and E have limited activity, while Cbz seems to retain its efficacy. Prospective studies that further examine sequential treatments are warranted.Entities:
Keywords: Abiraterone acetate; Cabazitaxel; Enzalutamide; Prostate cancer; Sequential therapy
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Year: 2015 PMID: 26052050 DOI: 10.1016/j.critrevonc.2015.04.010
Source DB: PubMed Journal: Crit Rev Oncol Hematol ISSN: 1040-8428 Impact factor: 6.312