Literature DB >> 26051807

A cationic gadolinium contrast agent for magnetic resonance imaging of cartilage.

Jonathan D Freedman1,2, Hrvoje Lusic3, Martin Wiewiorski2, Michelle Farley4,5, Brian D Snyder2, Mark W Grinstaff3,6,1.   

Abstract

A new cationic gadolinium contrast agent is reported for delayed gadolinium enhanced magnetic resonance imaging of cartilage (dGEMRIC). The agent partitions into the glycosaminoglycan rich matrix of articular cartilage, based on Donnan equilibrium theory, and its use enables imaging of the human cadaveric metacarpal phalangeal joint.

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Year:  2015        PMID： 26051807      PMCID： PMC4841792          DOI： 10.1039/c5cc03354c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  25 in total

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Authors:  Marie C Heffern; Lauren M Matosziuk; Thomas J Meade
Journal:  Chem Rev       Date:  2013-12-13       Impact factor: 60.622

Review 2.  Dendritic polymers in biomedical applications: from potential to clinical use in diagnostics and therapy.

Authors:  Salah-Eddine Stiriba; Holger Frey; Rainer Haag
Journal:  Angew Chem Int Ed Engl       Date:  2002-04-15       Impact factor: 15.336

Review 3.  Multimodality imaging probes: design and challenges.

Authors:  Angelique Louie
Journal:  Chem Rev       Date:  2010-05-12       Impact factor: 60.622

4.  Tantalum oxide nanoparticles for the imaging of articular cartilage using X-ray computed tomography: visualization of ex vivo/in vivo murine tibia and ex vivo human index finger cartilage.

Authors:  Jonathan D Freedman; Hrvoje Lusic; Brian D Snyder; Mark W Grinstaff
Journal:  Angew Chem Int Ed Engl       Date:  2014-06-30       Impact factor: 15.336

Review 5.  Designed synthesis of uniformly sized iron oxide nanoparticles for efficient magnetic resonance imaging contrast agents.

Authors:  Nohyun Lee; Taeghwan Hyeon
Journal:  Chem Soc Rev       Date:  2011-12-02       Impact factor: 54.564

6.  Nondestructive imaging of human cartilage glycosaminoglycan concentration by MRI.

Authors:  A Bashir; M L Gray; J Hartke; D Burstein
Journal:  Magn Reson Med       Date:  1999-05       Impact factor: 4.668

7.  Effect of contrast agent charge on visualization of articular cartilage using computed tomography: exploiting electrostatic interactions for improved sensitivity.

Authors:  Neel S Joshi; Prashant N Bansal; Rachel C Stewart; Brian D Snyder; Mark W Grinstaff
Journal:  J Am Chem Soc       Date:  2009-09-23       Impact factor: 15.419

8.  Targeted dendrimer-based contrast agents for articular cartilage assessment by MR imaging.

Authors:  C S Winalski; S Shortkroff; E Schneider; H Yoshioka; R V Mulkern; G M Rosen
Journal:  Osteoarthritis Cartilage       Date:  2008-01-15       Impact factor: 6.576

Review 9.  Biomedical applications of sodium MRI in vivo.

Authors:  Guillaume Madelin; Ravinder R Regatte
Journal:  J Magn Reson Imaging       Date:  2013-05-30       Impact factor: 4.813

Review 10.  Nanoparticle-based systems for T(1)-weighted magnetic resonance imaging contrast agents.

Authors:  Derong Zhu; Fuyao Liu; Lina Ma; Dianjun Liu; Zhenxin Wang
Journal:  Int J Mol Sci       Date:  2013-05-21       Impact factor: 5.923
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  6 in total

1.  dGEMRIC and CECT Comparison of Cationic and Anionic Contrast Agents in Cadaveric Human Metacarpal Cartilage.

Authors:  Jonathan D Freedman; Daniel J Ellis; Hrvoje Lusic; Gopal Varma; Aaron K Grant; Benjamin A Lakin; Brian D Snyder; Mark W Grinstaff
Journal:  J Orthop Res       Date:  2019-11-14       Impact factor: 3.494

Review 2.  Oligonucleotide Therapies in the Treatment of Arthritis: A Narrative Review.

Authors:  Susanne N Wijesinghe; Mark A Lindsay; Simon W Jones
Journal:  Biomedicines       Date:  2021-07-27

3.  Cartilage-penetrating nanocarriers improve delivery and efficacy of growth factor treatment of osteoarthritis.

Authors:  Brett C Geiger; Sheryl Wang; Robert F Padera; Alan J Grodzinsky; Paula T Hammond
Journal:  Sci Transl Med       Date:  2018-11-28       Impact factor: 17.956

Review 4.  Leveraging Electrostatic Interactions for Drug Delivery to the Joint.

Authors:  Shreedevi Kumar; Blanka Sharma
Journal:  Bioelectricity       Date:  2020-06-17

5.  Effect of intra-articular administration of superparamagnetic iron oxide nanoparticles (SPIONs) for MRI assessment of the cartilage barrier in a large animal model.

Authors:  Raphael Labens; Carola Daniel; Sarah Hall; Xin-Rui Xia; Tobias Schwarz
Journal:  PLoS One       Date:  2017-12-29       Impact factor: 3.240

6.  In vivo visualization of osteoarthritic hypertrophic lesions.

Authors:  Hai-Yu Hu; Ngee-Han Lim; Hans-Paul Juretschke; Danping Ding-Pfennigdorff; Peter Florian; Markus Kohlmann; Abdullah Kandira; Jens Peter von Kries; Joachim Saas; Karl A Rudolphi; K Ulrich Wendt; Hideaki Nagase; Oliver Plettenburg; Marc Nazare; Carsten Schultz
Journal:  Chem Sci       Date:  2015-08-12       Impact factor: 9.825
  6 in total

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