Literature DB >> 26051473

A novel azopyridine-based Ru(II) complex with GSH-responsive DNA photobinding ability.

Qian-Xiong Zhou1, Yue Zheng, Tian-Ji Wang, Yong-Jie Chen, Ke Li, Yang-Yang Zhang, Chao Li, Yuan-Jun Hou, Xue-Song Wang.   

Abstract

A novel azopyridine-based Ru(II) complex [Ru(bpy)2(L1)2](2+) (bpy = 2,2'-bipyridine, L1 = 4,4'-azopyridine) was designed and synthesized as a potential glutathione (GSH)-responsive photoactivated chemotherapy (PACT) agent, the DNA covalent binding capability of which can only be activated after GSH reduction and visible light irradiation.

Entities:  

Mesh:

Substances:

Year:  2015        PMID: 26051473     DOI: 10.1039/c5cc03291a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  3 in total

1.  An Overview Of Photosubstitution Reactions Of Ru(II) Imine Complexes And Their Application In Photobiology And Photodynamic Therapy.

Authors:  Jessica K White; Russell H Schmehl; Claudia Turro
Journal:  Inorganica Chim Acta       Date:  2016-06-18       Impact factor: 2.545

2.  Fluorination in enhancing photoactivated antibacterial activity of Ru(ii) complexes with photo-labile ligands.

Authors:  Weize Sun; Rena Boerhan; Na Tian; Yang Feng; Jian Lu; Xuesong Wang; Qianxiong Zhou
Journal:  RSC Adv       Date:  2020-07-03       Impact factor: 3.361

3.  Ligand-centred redox activation of inert organoiridium anticancer catalysts.

Authors:  Wen-Ying Zhang; Samya Banerjee; George M Hughes; Hannah E Bridgewater; Ji-Inn Song; Ben G Breeze; Guy J Clarkson; James P C Coverdale; Carlos Sanchez-Cano; Fortuna Ponte; Emilia Sicilia; Peter J Sadler
Journal:  Chem Sci       Date:  2020-05-15       Impact factor: 9.825

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.