| Literature DB >> 26051473 |
Qian-Xiong Zhou1, Yue Zheng, Tian-Ji Wang, Yong-Jie Chen, Ke Li, Yang-Yang Zhang, Chao Li, Yuan-Jun Hou, Xue-Song Wang.
Abstract
A novel azopyridine-based Ru(II) complex [Ru(bpy)2(L1)2](2+) (bpy = 2,2'-bipyridine, L1 = 4,4'-azopyridine) was designed and synthesized as a potential glutathione (GSH)-responsive photoactivated chemotherapy (PACT) agent, the DNA covalent binding capability of which can only be activated after GSH reduction and visible light irradiation.Entities:
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Year: 2015 PMID: 26051473 DOI: 10.1039/c5cc03291a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222