Literature DB >> 26051071

Metabolic regulation in model ascomycetes--adjusting similar genomes to different lifestyles.

Malcolm Whiteway1, Walters A Tebung2, Baharul I Choudhury2, Roberto Rodríguez-Ortiz2.   

Abstract

The related yeasts Saccharomyces cerevisiae and Candida albicans have similar genomes but very different lifestyles. These fungi have modified transcriptional and post-translational regulatory processes to adapt their similar genomes to the distinct biological requirements of the two yeasts. We review recent findings comparing the differences between these species, highlighting how they have achieved specialized metabolic capacities tailored to their lifestyles despite sharing similar genomes. Studying this transcriptional and post-transcriptional rewiring may improve our ability to interpret phenotype from genotype.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Candida albicans; Saccharomyces cerevisiae; fungal metabolism; transcriptional regulators; transcriptional rewiring

Mesh：

Substances：

Year:  2015        PMID： 26051071     DOI： 10.1016/j.tig.2015.05.002

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  12 in total

1.  Recurrent rewiring and emergence of RNA regulatory networks.

Authors:  Daniel Wilinski; Natascha Buter; Andrew D Klocko; Christopher P Lapointe; Eric U Selker; Audrey P Gasch; Marvin Wickens
Journal:  Proc Natl Acad Sci U S A       Date:  2017-03-20       Impact factor: 11.205

Review 2.  The importance of controlling mRNA turnover during cell proliferation.

Authors:  Sebastián Chávez; José García-Martínez; Lidia Delgado-Ramos; José E Pérez-Ortín
Journal:  Curr Genet       Date:  2016-03-23       Impact factor: 3.886

Review 3.  The rewiring of transcription circuits in evolution.

Authors:  Alexander D Johnson
Journal:  Curr Opin Genet Dev       Date:  2017-11-08       Impact factor: 5.578

4.  Reconfiguration of Transcriptional Control of Lysine Biosynthesis in Candida albicans Involves a Central Role for the Gcn4 Transcriptional Activator.

Authors:  Yumnam Priyadarshini; Krishnamurthy Natarajan
Journal:  mSphere       Date:  2016-01-22       Impact factor: 4.389

5.  Chemogenomic Profiling of the Fungal Pathogen Candida albicans.

Authors:  Yaolin Chen; Jaideep Mallick; Alaa Maqnas; Yuan Sun; Baharul I Choudhury; Pierre Côte; Lan Yan; Ting-Jun-Hong Ni; Yan Li; Dazhi Zhang; Roberto Rodríguez-Ortiz; Quan-Zhen Lv; Yuan-Ying Jiang; Malcolm Whiteway
Journal:  Antimicrob Agents Chemother       Date:  2018-01-25       Impact factor: 5.191

6.  An Intragenic Recombination Event Generates a Snf4-Independent Form of the Essential Protein Kinase Snf1 in Candida albicans.

Authors:  Austin Mottola; Joachim Morschhäuser
Journal:  mSphere       Date:  2019-06-19       Impact factor: 4.389

7.  Nuclear Ssr4 Is Required for the In Vitro and In Vivo Asexual Cycles and Global Gene Activity of Beauveria bassiana.

Authors:  Wei Shao; Qing Cai; Sen-Miao Tong; Sheng-Hua Ying; Ming-Guang Feng
Journal:  mSystems       Date:  2020-04-21       Impact factor: 6.496

8.  mSphere of Influence: Decoding Transcriptional Regulatory Networks To Illuminate the Mechanisms of Microbial Pathogenicity.

Authors:  Sadri Znaidi
Journal:  mSphere       Date:  2020-01-08       Impact factor: 4.389

9.  Put3 Positively Regulates Proline Utilization in Candida albicans.

Authors:  Walters Aji Tebung; Raha Parvizi Omran; Debra L Fulton; Joachim Morschhäuser; Malcolm Whiteway
Journal:  mSphere       Date:  2017-12-13       Impact factor: 4.389

10.  The Genomic Landscape of the Fungus-Specific SWI/SNF Complex Subunit, Snf6, in Candida albicans.

Authors:  Faiza Tebbji; Yaolin Chen; Adnane Sellam; Malcolm Whiteway
Journal:  mSphere       Date:  2017-11-15       Impact factor: 4.389
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