Literature DB >> 26048656

A reliable phenotypic assay for detection of ESBLs and AmpCs in MBL-producing gram-negative bacteria with the use of aminophenylboronic acid, dipicolinic acid and cloxacillin.

Saswati Datta1, Somdatta Chatterjee1, Shravani Mitra1, Sulagna Basu2.   

Abstract

ESBLs and AmpCs may escape detection when they coexist with metallo-β-lactamases such as New Delhi Metallo-β-lactamases-1. In this study a combination disk assay was established using cefotaxime, cefotaxime/clavulanic acid, cefotaxime/clavulanic acid/cloxacillin, cefoxitin and cefoxitin/phenylboronic acid/cloxacillin on Mueller Hinton agar supplemented with dipicolinic acid for determination of β-lactamases in the presence of NDM-1.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cloxacillin; Combination disk test; Dipicolinic acid; Gram-negative bacteria; NDM-1; Phenylboronic acid

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Year:  2015        PMID： 26048656     DOI： 10.1016/j.mimet.2015.05.028

Source DB:  PubMed          Journal:  J Microbiol Methods        ISSN： 0167-7012            Impact factor:   2.363


  1 in total

1.  Carbapenem Resistance in Acinetobacter baumannii and Other Acinetobacter spp. Causing Neonatal Sepsis: Focus on NDM-1 and Its Linkage to ISAba125.

Authors:  Somdatta Chatterjee; Saswati Datta; Subhasree Roy; Lavanya Ramanan; Anindya Saha; Rajlakshmi Viswanathan; Tapas Som; Sulagna Basu
Journal:  Front Microbiol       Date:  2016-08-08       Impact factor: 5.640
  1 in total

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