Literature DB >> 2604709

Kallikrein-gene expression in the rat gastrointestinal tract.

P J Fuller1, K Verity, B A Matheson, J A Clements.   

Abstract

The serine proteinase glandular kallikrein has been demonstrated in the gastrointestinal tract, although there is some doubt as to whether it is synthesized there or derives from exocrine-gland secretions. Using a rat pancreatic kallikrein cRNA probe we have demonstrated kallikrein-like gene expression in the corpus, duodenum, jejunum, ileum, caecum and colon, and compared the pattern of expression with that of the gastrointestinal peptides somatostatin, gastrin and glucagon. In addition, using a panel of oligonucleotide probes specific for various members of the rat kallikrein-gene family, we have shown that the kallikrein-like gene expressed appears to be expressed as true kallikrein.

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Year:  1989        PMID： 2604709      PMCID： PMC1133556          DOI： 10.1042/bj2640133

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  36 in total

Review 1.  Kallikreins (kininogenases)--a group of serine proteases with bioregulatory actions.

Authors:  M Schachter
Journal:  Pharmacol Rev       Date:  1979-03       Impact factor: 25.468

2.  Immunological identification of rat tissue kallikrein cDNA and characterization of the kallikrein gene family.

Authors:  W L Gerald; J Chao; L Chao
Journal:  Biochim Biophys Acta       Date:  1986-02-24

3.  Specific cleavage of beta-LPH and ACTH by tonin: release of an opiate-like peptide beta-LPH (61-78).

Authors:  N G Seidah; J S Chan; G Mardini; S Benjannet; M Chrétien; R Boucher; J Genest
Journal:  Biochem Biophys Res Commun       Date:  1979-02-28       Impact factor: 3.575

4.  Tissue-specific expression of kallikrein-related genes in the rat.

Authors:  P L Ashley; R J MacDonald
Journal:  Biochemistry       Date:  1985-08-13       Impact factor: 3.162

5.  Intestinal kallikrein activity is reduced in a bypassed segment of the small intestine in the rat.

Authors:  D W Skagen; K J Andersen
Journal:  Comp Biochem Physiol A Comp Physiol       Date:  1986

6.  Human urinary kallikrein converts inactive to active renin and is a possible physiological activator of renin.

Authors:  J E Sealey; S A Atlas; J H Laragh; N B Oza; J W Ryan
Journal:  Nature       Date:  1978-09-14       Impact factor: 49.962

7.  Nucleotide sequence and evolution of a mammalian alpha-tubulin messenger RNA.

Authors:  I R Lemischka; S Farmer; V R Racaniello; P A Sharp
Journal:  J Mol Biol       Date:  1981-09-05       Impact factor: 5.469

8.  Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.

Authors:  H Aviv; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205

9.  Human kidney kallikrein: cDNA cloning and sequence analysis.

Authors:  A R Baker; J Shine
Journal:  DNA       Date:  1985-12

10.  Purification and properties of rat stomach kallikrein.

Authors:  K Uchida; M Niinobe; H Kato; S Fujii
Journal:  Biochim Biophys Acta       Date:  1980-08-07
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  4 in total

Review 1.  Molecular aspects of kallikrein and kininogen in the maturing kidney.

Authors:  S S el-Dahr; S Dipp
Journal:  Pediatr Nephrol       Date:  1993-10       Impact factor: 3.714

2.  Evolution of the rat kallikrein gene family: gene conversion leads to functional diversity.

Authors:  D R Wines; J M Brady; E M Southard; R J MacDonald
Journal:  J Mol Evol       Date:  1991-06       Impact factor: 2.395

Review 3.  Development biology of the renal kallikrein-kinin system.

Authors:  S S el-Dahr
Journal:  Pediatr Nephrol       Date:  1994-10       Impact factor: 3.714

4.  Molecular cloning, purification and in situ localization of human colon kallikrein.

Authors:  L M Chen; G P Richards; L Chao; J Chao
Journal:  Biochem J       Date:  1995-04-15       Impact factor: 3.857
  4 in total

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