Literature DB >> 26046999

Hibernoma.

Geetika Klevos1, Jean Jose, Juan Pretell-Mazzini, Sheila Conway.   

Abstract

Hibernomas are rare benign soft-tissue tumors containing brown fat. Clinically, they present as slow-growing, painless soft-tissue masses. Physical examination usually reveals a palpable, solitary, soft, and rubbery mass within the subcutaneous fat, which is freely mobile and not attached to deep layers. Conventional radiography may show a radiolucent mass without internal mineralization or associated osseous abnormalities. Sonographically, hibernomas are well-circumscribed, solid, hyperechoic masses with increased internal vascular flow. Computed tomography shows internal septations and low attenuation values, between those of fat and muscle. Hibernomas are usually hyperintense to skeletal muscle on T1-weighted magnetic resonance imaging (MRI) but slightly hypointense to subcutaneous fat. On T2-weighted images, high signal intensity similar to that of subcutaneous fat is typical. Hibernomas demonstrate intense fluorine-18 fluorodeoxyglucose uptake on positron emission tomography, because, unlike other adipogenic tumors, they contain abundant mitochondria and are highly metabolically active. Complete surgical excision is the treatment of choice, and is considered curative.

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Year:  2015        PMID: 26046999

Source DB:  PubMed          Journal:  Am J Orthop (Belle Mead NJ)        ISSN: 1078-4519


  2 in total

Review 1.  Brown Adipose Tissue: New Challenges for Prevention of Childhood Obesity. A Narrative Review.

Authors:  Elvira Verduci; Valeria Calcaterra; Elisabetta Di Profio; Giulia Fiore; Federica Rey; Vittoria Carlotta Magenes; Carolina Federica Todisco; Stephana Carelli; Gian Vincenzo Zuccotti
Journal:  Nutrients       Date:  2021-04-24       Impact factor: 5.717

2.  Testicular Pouch Hibernoma: A Case Report.

Authors:  Eric Martinez Lino; Waldomiro Camargo; Beatriz Varanda Rizzo Teixeira; Eduardo Sonego de Toledo; Ana Clara Nagle Spessoto; Maria Fernanda Warick Facio; Fernando Nestor Facio; Luís Cesar Fava Spessoto
Journal:  Cureus       Date:  2021-12-26
  2 in total

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