Literature DB >> 26046644

Rag Ubiquitination Recruits a GATOR1: Attenuation of Amino Acid-Induced mTORC1 Signaling.

Diane C Fingar1.   

Abstract

In recent issues of Molecular Cell, two reports identify that K63-linked RagA polyubiquitination and subsequent recruitment of GATOR1, a complex with GAP activity toward RagA/B GTPases, can attenuate amino acid-induced mTORC1 signaling.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2015        PMID: 26046644     DOI: 10.1016/j.molcel.2015.05.029

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  1 in total

1.  Phosphorylation by mTORC1 stablizes Skp2 and regulates its oncogenic function in gastric cancer.

Authors:  Qirong Geng; Jianjun Liu; Zhaohui Gong; Shangxiang Chen; Shuai Chen; Xiaoxing Li; Yue Lu; Xiaofeng Zhu; Hui-Kuan Lin; Dazhi Xu
Journal:  Mol Cancer       Date:  2017-04-26       Impact factor: 27.401

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.