Literature DB >> 26046433

It's a SMAD/SMAD World.

Cullen Taniguchi1, Anirban Maitra2.   

Abstract

DPC4/SMAD4 mutations are associated with aggressive pancreatic cancer. In this issue of Cell, Whittle et al. demonstrate that Runx3 expression combined with Dpc4/Smad4 status can predict the metastatic propensity of pancreatic tumors, providing valuable guidance for personalized therapy for patients with pancreatic cancer.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 26046433     DOI: 10.1016/j.cell.2015.05.030

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  5 in total

1.  Genomic Landscape of Pancreatic Adenocarcinoma in Younger versus Older Patients: Does Age Matter?

Authors:  Irit Ben-Aharon; Moshe Elkabets; Raphael Pelossof; Kenneth H Yu; Christine A Iacubuzio-Donahue; Steven D Leach; Maeve A Lowery; Karyn A Goodman; Eileen M O'Reilly
Journal:  Clin Cancer Res       Date:  2019-01-07       Impact factor: 12.531

2.  Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer.

Authors:  Tara N Fujimoto; Lauren E Colbert; Yanqing Huang; Jessica M Molkentine; Amit Deorukhkar; Laura Baseler; Meifang Yu; Daniel Lin; Sonal Gupta; Peter K Cabeceiras; Charles V Kingsley; Ramesh C Tailor; Gabriel O Sawakuchi; Eugene J Koay; Helen Piwnica-Worms; Anirban Maitra; Cullen M Taniguchi
Journal:  Cancer Res       Date:  2019-05-01       Impact factor: 12.701

3.  A microRNA signature of response to erlotinib is descriptive of TGFβ behaviour in NSCLC.

Authors:  Madeline Krentz Gober; James P Collard; Katherine Thompson; Esther P Black
Journal:  Sci Rep       Date:  2017-06-23       Impact factor: 4.379

Review 4.  Clinicopathological significance of SMAD4 loss in pancreatic ductal adenocarcinomas: a systematic review and meta-analysis.

Authors:  Jin-Dao Wang; Ketao Jin; Xiao-Ying Chen; Jie-Qing Lv; Ke-Wei Ji
Journal:  Oncotarget       Date:  2017-03-07

5.  Twist1-related miR-26b-5p suppresses epithelial-mesenchymal transition, migration and invasion by targeting SMAD1 in hepatocellular carcinoma.

Authors:  Yong Wang; Baocun Sun; Xiulan Zhao; Nan Zhao; Ran Sun; Dongwang Zhu; Yanhui Zhang; Yanlei Li; Qiang Gu; Xueyi Dong; Meili Wang; Jindan An
Journal:  Oncotarget       Date:  2016-04-26
  5 in total

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