Haifen Ma1, Maofen Jiang1, Weihua Xiao1. 1. Department of Pathology, Beilun People's Hospital Ningbo 315800, Zhejiang Province, China.
Abstract
OBJECTIVES: The stroma-rich variant of hyaline-vascular type of Castleman's disease (SR-HVCD) should be differentiated from vascular or follicular dendritic reticulum cell neoplasms. In this paper, we present a rare case of HVCD. We also suspect a possible association between SR-HVCD and calcifying fibrous pseudotumor. METHODS: A 34-year-old man was found an abdominal mass by computed tomography (CT) in a general health checkup. The mass was resected from the mesenteric root. The specimens were evaluated for detailed characterizations through gross examination, microscopy and immunohistochemistry. RESULTS: The mass showed histologic patterns and immunohistochemical results of HVCD with significant angiomyoid proliferations, collagenation and focal calcification. Histologically, stromal elements of HVCD in our case were similar to those of a calcifying fibrous pseudotumour. CONCLUSIONS: A possible association was suspected between SR-HVCD and calcifying fibrous pseudotumor. To the best of our knowledge, this is the fourth report of describing an association between the two diseases in the English literature.
OBJECTIVES: The stroma-rich variant of hyaline-vascular type of Castleman's disease (SR-HVCD) should be differentiated from vascular or follicular dendritic reticulum cell neoplasms. In this paper, we present a rare case of HVCD. We also suspect a possible association between SR-HVCD and calcifying fibrous pseudotumor. METHODS: A 34-year-old man was found an abdominal mass by computed tomography (CT) in a general health checkup. The mass was resected from the mesenteric root. The specimens were evaluated for detailed characterizations through gross examination, microscopy and immunohistochemistry. RESULTS: The mass showed histologic patterns and immunohistochemical results of HVCD with significant angiomyoid proliferations, collagenation and focal calcification. Histologically, stromal elements of HVCD in our case were similar to those of a calcifying fibrous pseudotumour. CONCLUSIONS: A possible association was suspected between SR-HVCD and calcifying fibrous pseudotumor. To the best of our knowledge, this is the fourth report of describing an association between the two diseases in the English literature.