Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Expansion of the hematopoietic stem cell compartment is necessary but not sufficient for gain-of-function mutant p53 R248Q to accelerate lymphomagenesis.

Literature DB >> 26045050

Expansion of the hematopoietic stem cell compartment is necessary but not sufficient for gain-of-function mutant p53 R248Q to accelerate lymphomagenesis.

A R Yallowitz¹, W Hanel¹, U M Moll¹.

Abstract

Entities: Gene Mutation

Mesh：

Substances：

Year: 2015 PMID： 26045050 PMCID： PMC4495365 DOI： 10.1038/cdd.2015.63

Source DB: PubMed Journal: Cell Death Differ ISSN： 1350-9047 Impact factor: 15.828

Keyword Cloud
References

× No keyword cloud information.

7 in total

1. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis.

Authors: Cyril Quivoron; Lucile Couronné; Véronique Della Valle; Cécile K Lopez; Isabelle Plo; Orianne Wagner-Ballon; Marcio Do Cruzeiro; Francois Delhommeau; Bertrand Arnulf; Marc-Henri Stern; Lucy Godley; Paule Opolon; Hervé Tilly; Eric Solary; Yannis Duffourd; Philippe Dessen; Hélène Merle-Beral; Florence Nguyen-Khac; Michaëla Fontenay; William Vainchenker; Christian Bastard; Thomas Mercher; Olivier A Bernard
Journal: Cancer Cell Date: 2011-06-30 Impact factor: 31.743

Review 2. Clonal evolution of acute leukemia genomes.

Authors: M Jan; R Majeti
Journal: Oncogene Date: 2012-02-20 Impact factor: 9.867

Review 3. The p53 pathway in hematopoiesis: lessons from mouse models, implications for humans.

Authors: Vinod Pant; Alfonso Quintás-Cardama; Guillermina Lozano
Journal: Blood Date: 2012-09-27 Impact factor: 22.113

4. Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia.

Authors: Yoshikane Kikushige; Fumihiko Ishikawa; Toshihiro Miyamoto; Takahiro Shima; Shingo Urata; Goichi Yoshimoto; Yasuo Mori; Tadafumi Iino; Takuji Yamauchi; Tetsuya Eto; Hiroaki Niiro; Hiromi Iwasaki; Katsuto Takenaka; Koichi Akashi
Journal: Cancer Cell Date: 2011-08-16 Impact factor: 31.743

Expansion of the hematopoietic stem cell compartment is necessary but not sufficient for gain-of-function mutant p53 R248Q to accelerate lymphomagenesis.

1. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis.

Review 2. Clonal evolution of acute leukemia genomes.

Review 3. The p53 pathway in hematopoiesis: lessons from mouse models, implications for humans.

4. Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia.

5. Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis.

6. Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment.

7. Transgenic mice with hematopoietic and lymphoid specific expression of Cre.