Literature DB >> 26043213

Cellular prognostic markers in hepatocellular carcinoma.

Luigi Buonaguro, Maria Tagliamonte, Annacarmen Petrizzo, Elvira Damiano, Maria Lina Tornesello, Franco M Buonaguro.   

Abstract

Hepatocellular carcinoma (HCC) is one of the five big killers worldwide and is frequently associated with chronic hepatitis B and C virus (HBV and HCV) infections. Tumor microenvironment consists of a complex network of cells and factors that plays a key role in the tumor progression and prognosis. This is true also for HCC. Several studies have shown strikingly strong correlation between HCC clinical prognosis and intratumoral infiltration of cells affecting tumor growth, invasion, angiogenesis and metastasis. None of such cells is yet validated for routine diagnostic and prognostic assessment. The present review aims at providing a state-of-the-art of such studies.

Entities:  

Keywords:  Tregs; cancer-associated fibroblasts; hepatic stellate cells; hepatic stem/progenitor cells; hepatocellular carcinoma; macrophages; neutrophils; prognostic markers

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Year:  2015        PMID： 26043213     DOI： 10.2217/fon.15.39

Source DB:  PubMed          Journal:  Future Oncol        ISSN： 1479-6694            Impact factor:   3.404


  8 in total

1.  U/G SNP rs111904020 in 3'UTR of STAT3 regulated by miR-214 promotes hepatocellular carcinoma development in Chinese population.

Authors:  Ye Fan; Xiaofeng Qian; Chuanyong Zhang
Journal:  Tumour Biol       Date:  2016-09-12

2.  Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as predictors of tumor response in hepatocellular carcinoma after DEB-TACE.

Authors:  Isabel Theresa Schobert; Lynn Jeanette Savic; Julius Chapiro; Khaled Bousabarah; Evan Chen; Fabian Laage-Gaupp; Jonathan Tefera; Nariman Nezami; MingDe Lin; Jeffrey Pollak; Todd Schlachter
Journal:  Eur Radiol       Date:  2020-05-19       Impact factor: 5.315

3.  Application of the Immunoscore as prognostic tool for hepatocellular carcinoma.

Authors:  Annacarmen Petrizzo; Luigi Buonaguro
Journal:  J Immunother Cancer       Date:  2016-11-15       Impact factor: 13.751

Review 4.  Cellular prognostic markers in hepatitis-related hepatocellular carcinoma.

Authors:  A Petrizzo; A Mauriello; M L Tornesello; F M Buonaguro; M Tagliamonte; L Buonaguro
Journal:  Infect Agent Cancer       Date:  2018-03-27       Impact factor: 2.965

5.  Integrated Proteomics and Bioinformatics to Identify Potential Prognostic Biomarkers in Hepatocellular Carcinoma.

Authors:  Qifan Zhang; Zhen Xiao; Shibo Sun; Kai Wang; Jianping Qian; Zhonglin Cui; Tao Tao; Jie Zhou
Journal:  Cancer Manag Res       Date:  2021-03-11       Impact factor: 3.989

6.  The prognostic significance of inflammation-immunity-nutrition score on postoperative survival and recurrence in hepatocellular carcinoma patients.

Authors:  Yuxin Liang; Zilong Zhang; Deyuan Zhong; Chunyou Lai; Zonglin Dai; Haibo Zou; Tianhang Feng; Jin Shang; Ying Shi; Xiaolun Huang
Journal:  Front Oncol       Date:  2022-08-09       Impact factor: 5.738

Review 7.  Molecular alterations in hepatocellular carcinoma associated with hepatitis B and hepatitis C infections.

Authors:  Maria Lina Tornesello; Luigi Buonaguro; Francesco Izzo; Franco M Buonaguro
Journal:  Oncotarget       Date:  2016-05-03

8.  Systemic Inflammation Response Index is a Prognostic Risk Factor in Patients with Hepatocellular Carcinoma Undergoing TACE.

Authors:  Jun-Xiang Li; Peng-Fei Pang; Tian-Cheng Wang; Tian-Zhi An
Journal:  Risk Manag Healthc Policy       Date:  2021-06-21
  8 in total

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