Literature DB >> 26042942

Click-engineered, bioresponsive, drug-loaded PEG spheres.

Heng Pho Yap1, Angus P R Johnston1, Georgina K Such1, Yan Yan1, Frank Caruso2.   

Abstract

A click-chemistry approach to synthesize bioresponsive poly(ethylene glycol acrylate) particles is described. The particles are loaded with a model anticancer drug (doxorubicin, DOX), and undergo simultaneous particle deconstruction and DOX release upon specific activation by the simulated environment of the cellular cytoplasm.
Copyright © 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Layer‐by‐layer assembly; click chemistry; drug delivery; polymer capsules

Year:  2009        PMID： 26042942     DOI： 10.1002/adma.200900421

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  3 in total

1.  Click-Engineered, Bioresponsive, and Versatile Particle-Protein-Dye System.

Authors:  Mary K Burdette; Ragini Jenkins; Yuriy P Bandera; Haley Jones; Isabell K Foulger; Ashley Dickey; Anna-Liisa Nieminen; Stephen H Foulger
Journal:  ACS Appl Bio Mater       Date:  2019-07-01

2.  Biocompatible, photo-responsive layer-by-layer polymer nanocapsules with an oil core: in vitro and in vivo study.

Authors:  Chiara Di Cicco; Raffaele Vecchione; Vincenzo Quagliariello; Alice Busato; Immacolata Tufano; Emiliano Bedini; Marco Gerosa; Andrea Sbarbati; Federico Boschi; Pasquina Marzola; Nicola Maurea; Paolo A Netti
Journal:  J R Soc Interface       Date:  2022-02-23       Impact factor: 4.118

3.  Ultralow protein adsorbing coatings from clickable PEG nanogel solutions: benefits of attachment under salt-induced phase separation conditions and comparison with PEG/albumin nanogel coatings.

Authors:  Casey D Donahoe; Thomas L Cohen; Wenlu Li; Peter K Nguyen; John D Fortner; Robi D Mitra; Donald L Elbert
Journal:  Langmuir       Date:  2013-03-11       Impact factor: 3.882
  3 in total

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