Prashanth Giridhar1, Supriya Mallick2, M A Laviraj1, Suman Bhasker1. 1. Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi, India. 2. Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi, India. drsupriyamallick@gmail.com.
Abstract
INTRODUCTION: Esthesioneuroblastoma is a rare tumour of the sino-nasal tract. One-third cases present with intracranial extension. However, treatment options are limited for such cases. METHODOLOGY: We herein report a case with large intracranial extension treated with Induction chemotherapy, de-bulking surgery, and image guided intensity modulated radiotherapy. RESULTS: The patient was treated with IGIMRT technique to a dose of 64 Gy in 32 fractions. Cone bean CT verification was done twice a week to eliminate set up error. The patient achieved complete resolution of the disease and was disease free 6 months after completion of treatment. CONCLUSION: IGIMRT even after a de-bulking surgery may help to achieve long-term disease control for patients with large intracranial extension with minimal morbidity.
INTRODUCTION:Esthesioneuroblastoma is a rare tumour of the sino-nasal tract. One-third cases present with intracranial extension. However, treatment options are limited for such cases. METHODOLOGY: We herein report a case with large intracranial extension treated with Induction chemotherapy, de-bulking surgery, and image guided intensity modulated radiotherapy. RESULTS: The patient was treated with IGIMRT technique to a dose of 64 Gy in 32 fractions. Cone bean CT verification was done twice a week to eliminate set up error. The patient achieved complete resolution of the disease and was disease free 6 months after completion of treatment. CONCLUSION: IGIMRT even after a de-bulking surgery may help to achieve long-term disease control for patients with large intracranial extension with minimal morbidity.
Authors: G Benfari; M Fusconi; A Ciofalo; A Gallo; G Altissimi; T Celani; M De Vincentiis Journal: Acta Otorhinolaryngol Ital Date: 2008-12 Impact factor: 2.124
Authors: Snehal G Patel; Bhuvanesh Singh; Hilda E Stambuk; Diane Carlson; Patrick G Bridger; Giulio Cantu; Anthony D Cheesman; Paul Donald; Dan Fliss; Patrick Gullane; Shin-Etsu Kamata; Ivo Janecka; Luiz P Kowalski; Dennis H Kraus; Paul A Levine; Luiz R Medina; Sultan Pradhan; Victor Schramm; Carl Snyderman; William I Wei; Jatin P Shah Journal: J Neurol Surg B Skull Base Date: 2012-06