Achim Fieß1, J Bauer2, C Schindel3, M Knuf2, S Dithmar4. 1. Augenklinik des Klinikums Wiesbaden, Dr. Horst-Schmidt-Kliniken, Ludwig-Erhard-Straße 100, 65199, Wiesbaden, Deutschland. Achim.Fiess@hsk-wiesbaden.de. 2. Klinik für Kinder und Jugendliche, Dr. Horst-Schmidt-Kliniken, Wiesbaden, Deutschland. 3. Institut für Labordiagnostik und Hygiene, Dr. Horst-Schmidt-Kliniken, Wiesbaden, Deutschland. 4. Augenklinik des Klinikums Wiesbaden, Dr. Horst-Schmidt-Kliniken, Ludwig-Erhard-Straße 100, 65199, Wiesbaden, Deutschland.
Abstract
BACKGROUND: This case report describes an extremely rare Candida lens abscess in a premature infant (gestational age 24 weeks at birth). CASE REPORT: After birth the infant suffered from Candida sepsis which was successfully treated with an antifungal medication. The patient was referred at the age of 6 months because of greyish alterations in the pupils but an absence of other symptoms. The examination with the patient under general anesthesia revealed a grey pupillary membrane and behind it a whitish swollen lens. A lensectomy was performed. The vitreous body was inconspicuous. Candida albicans was identified microbiologically. CONCLUSIONS: In preterm infants dissemination of pathogens into the lens through the vascular coat of the lens is possible, which after regression of the coat is no longer accessible to systemic treatment and may thus be manifested as delayed abscess formation.
BACKGROUND: This case report describes an extremely rare Candida lens abscess in a premature infant (gestational age 24 weeks at birth). CASE REPORT: After birth the infant suffered from Candida sepsis which was successfully treated with an antifungal medication. The patient was referred at the age of 6 months because of greyish alterations in the pupils but an absence of other symptoms. The examination with the patient under general anesthesia revealed a grey pupillary membrane and behind it a whitish swollen lens. A lensectomy was performed. The vitreous body was inconspicuous. Candida albicans was identified microbiologically. CONCLUSIONS: In preterm infants dissemination of pathogens into the lens through the vascular coat of the lens is possible, which after regression of the coat is no longer accessible to systemic treatment and may thus be manifested as delayed abscess formation.
Authors: Rita Singh-Parikshak; Erick D Bothun; Roseanne Superstein; Monte Del Monte; Steven Archer; Mark W Johnson Journal: Arch Ophthalmol Date: 2004-09