Literature DB >> 26037678

[A case of metachronal testicular tumor eight years after medical treatment of extragonadal germ cell tumor].

Makoto Tanio1, Yoshitaka Aoki1, Hisato Kobayashi1, Satoshi Yokoi1, Hideaki Ito1, Nobuyuki Oyama1, Hironobu Akino1, Osamu Yokoyama1.   

Abstract

A 22-year-old man was admitted to our hospital complaining of a left cervical mass. Computed tomography (CT) showed multiple enlarged lymph nodes at the left cervical vein and para-aortic areas. Histological examination of a biopsy indicated an embryonal carcinoma. The levels of human β-chorionic gonadotropin (β-HCG) and lactic dehydrogenase (LDH) were both elevated. Ultrasonography revealed testicular calcification, but there were no findings on magnetic resonance imaging (MRI). The patient was diagnosed as having an extragonadal germ cell tumor. After four courses of chemotherapy with BEP protocol (bleomycin, etoposide and cisplatin), retroperineal lymph node dissection (RPLND) was performed and there was no involvement of the viable cells in the resected lymph nodes. Eight years after chemotherapy, he noticed an enlargement of his left scrotum without pain. β-HCG was again elevated. A unilateral high orchiectomy was performed, and histology revealed a seminoma. He was staged as pT1N0M0S0. Six months later he remains disease-free.

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Year:  2015        PMID: 26037678

Source DB:  PubMed          Journal:  Hinyokika Kiyo        ISSN: 0018-1994


  1 in total

1.  Late testicular relapse two decades after primary extragonadal germ cell tumor with uncommon metastases: a case report.

Authors:  Motoi Tobiume; Shigeyuki Aoki; Genya Nishikawa; Hiroyuki Muramatsu; Kenzo Ono; Shingo Morinaga; Koji Hara; Natsuko Ando; Keiko Ono; Chie Nishibata; Ayumi Hidano; Makiko Nakagawa; Ikumi Takahashi; Kanae Matsubara; Yoshiaki Yamada
Journal:  J Med Case Rep       Date:  2021-02-05
  1 in total

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