Literature DB >> 26037217

Dysplastic nevus: Fact and fiction.

Cliff O Rosendahl1, Jane M Grant-Kels2, Syril Keena T Que3.   

Abstract

The term "dysplastic nevus" (DN) implies that this nevus exists as a distinct and defined entity of potential detriment to its host. We examine the current data, which suggest that this entity exists as histologically and possibly genetically different from common nevus, with some overlapping features. Studies show that a melanoma associated with a nevus is just as likely to arise in a common nevus as in DN. Furthermore, there is no evidence that a histologically defined DN evolves into a melanoma or that the presence of 1 or more DN on an individual patient confers any increased melanoma risk. We suggest that the term "dysplastic nevus" be abandoned so that the focus can shift to confirmed and relevant indicators of melanoma risk, including high nevus counts and large nevus size.
Copyright © 2015 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  B-K mole syndrome; BRAF; common nevus; congenital melanocytic nevus; cyclin-dependent kinase inhibitor 2A (CDKN2A); dysplastic nevus; familial atypical multiple-mole melanoma; melanoma; p16, p53

Mesh:

Year:  2015        PMID: 26037217     DOI: 10.1016/j.jaad.2015.04.029

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  5 in total

1.  Does an increased number of moles correlate to a higher risk of melanoma?

Authors:  Mehul Bhatt; Adam Nabatian; David Kriegel; Hooman Khorasani
Journal:  Melanoma Manag       Date:  2016-05-19

2.  Dermoscopy of a Spark's nevus.

Authors:  Giovanni Biondo; Matteo Gnone; Simona Sola; Carlotta Pastorino; Cesare Massone
Journal:  Dermatol Pract Concept       Date:  2018-04-30

3.  Clinical, pathological and dermoscopic phenotype of MITF p.E318K carrier cutaneous melanoma patients.

Authors:  Giulia Ciccarese; Bruna Dalmasso; William Bruno; Paola Queirolo; Lorenza Pastorino; Virginia Andreotti; Francesco Spagnolo; Enrica Tanda; Giovanni Ponti; Cesare Massone; Francesco Drago; Aurora Parodi; Giovanni Ghigliotti; Maria Antonietta Pizzichetta; Paola Ghiorzo
Journal:  J Transl Med       Date:  2020-02-13       Impact factor: 5.531

4.  The "Dysplastic Nevus" Conundrum: A Look Back, a Peek Forward.

Authors:  Catherine M Stefanato
Journal:  Dermatopathology (Basel)       Date:  2018-04-20

5.  Spitz Nevus with Features of Clark Nevus, So-Called SPARK Nevus: Case Series Presentation with Emphasis on Cytological and Histological Features.

Authors:  Antonietta Cimmino; Gerardo Cazzato; Anna Colagrande; Eugenio Maiorano; Lucia Lospalluti; Giuseppe Ingravallo; Leonardo Resta
Journal:  Dermatopathology (Basel)       Date:  2021-12-01
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.