| Literature DB >> 26036135 |
K S Afanasieva, S V Prylutska, A V Lozovik, K I Bogutska, A V Sivolob, Yu I Prylutskyy, U Ritter, P Scharff.
Abstract
The self-ordering of C60 fullerene, doxorubicin and their mixture precipitated from aqueous solutions was investigated using atomic-force microscopy. The results suggest the complexation between the two compounds. The genotoxicity of doxorubicin in complex with C60 fullerene (C 60+Dox) was evaluated in vitro with comet assay using human lymphocytes. The obtained results show that the C60 fullerene prevents the toxic effect of Dox in normal cells and, thus, C60+Dox complex might be proposed for biomedical application.Entities:
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Year: 2015 PMID： 26036135
Source DB: PubMed Journal: Ukr Biochem J ISSN： 2409-4943