Literature DB >> 26035982

Clinical and radiological indicators of severity in patients with acute pancreatitis.

Jorge Álvarez, Pablo Castro, Maria Fernández, Beatriz Mcmullen, Carmen Rodríguez, Jorge Vera.   

Abstract

UNLABELLED: The purpose of this study was to estimate the degree of association between clinical (Ranson criteria) and radiological variables (Abdominal CT scan) with degree of severity in patients with a diagnosis of acute pancreatitis.
METHOD: All patients discharged with the diagnosis of acute pancreatitis from January 1, 2010 through December 31, 2012 in a community hospital were selected (N=174). The following variables were studied: sex; age; weight; height; admission and discharge dates; presence of several chronic conditions; laboratory results included in Ranson criteria; abdominal CT category; outcome, including fatality surgery, and other complications. Analysis included descriptive statistics and Risk-Ratios for complications for different groups of subjects, using clinical and radiological criteria.
RESULTS: The incidence rate of complications, including fatality, surgery and organ failure was 36.2%. Factors that showed significant associations with the risk of complication on crude analysis were gallbladder disease with a RR=1.78 ($95% CI: 1.22, 2.60) and abnormal abdominal CT with a RR=1.85 (95% CI: 1.11, 3.07). with multivariate analysis, gallbladder disease, abnormal abdominal CT, and presence of 3 or more Ranson's criteria showed increased risk for complications, but the results did not reach statistical significance. DISCUSSION: The factors that seemed to be associated with increased rate of complications in subjects with acute pancreatitis were gallbladder disease, abnormal abdominal CT, and 3 or more Ranson's criteria. The Results did not show statistical significance probably because of low statistical power of the study.

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Mesh:

Year:  2015        PMID: 26035982

Source DB:  PubMed          Journal:  Bol Asoc Med P R        ISSN: 0004-4849


  4 in total

1.  Interleukin-10 -1082A/G polymorphism is associated with the development of acute pancreatitis in a Chinese population.

Authors:  Feng Cai; Ning Cui; Hongyan Ma; Xueli Wang; Guihong Qiao; Danping Liu
Journal:  Int J Clin Exp Pathol       Date:  2015-11-01

2.  Interleukin-10 gene rs1800896 polymorphism increases risk of acute pancreatitis.

Authors:  Hongmei Zhou; Ailing Liu; Bingzhi Zhou; Cunxin Zhao; Guangjun Jin
Journal:  Medicine (Baltimore)       Date:  2017-12       Impact factor: 1.817

3.  Association between vitamin D receptor polymorphisms and acute pancreatitis: A protocol for systematic review and meta analysis.

Authors:  Xiaofeng Li; Xianghai Gan; Junzuo Gong; Tianyi Mou; Hua Zhou; Mengqin Li
Journal:  Medicine (Baltimore)       Date:  2021-04-23       Impact factor: 1.817

4.  Elevated Serum miR-7, miR-9, miR-122, and miR-141 Are Noninvasive Biomarkers of Acute Pancreatitis.

Authors:  Pan Lu; Feng Wang; Jia Wu; Cheng Wang; Jing Yan; Zhuo-Ling Li; Jia-Xi Song; Jun-Jun Wang
Journal:  Dis Markers       Date:  2017-12-03       Impact factor: 3.434

  4 in total

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