Literature DB >> 26035007

The hybrid synthetic microdata platform: a method for statistical disclosure control.

Joël Kuiper1,2, Edwin R van den Heuvel1, Morris A Swertz2,3.   

Abstract

Owners of biobanks are in an unfortunate position: on the one hand, they need to protect the privacy of their participants, whereas on the other, their usefulness relies on the disclosure of the data they hold. Existing methods for Statistical Disclosure Control attempt to find a balance between utility and confidentiality, but come at a cost for the analysts of the data. We outline an alternative perspective to the balance between confidentiality and utility. By combining the generation of synthetic data with the automated execution of data analyses, biobank owners can guarantee the privacy of their participants, yet allow the analysts to work in an unrestricted manner.

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Year:  2015        PMID: 26035007      PMCID: PMC4559158          DOI: 10.1089/bio.2014.0069

Source DB:  PubMed          Journal:  Biopreserv Biobank        ISSN: 1947-5543            Impact factor:   2.300


  8 in total

Review 1.  Weaving technology and policy together to maintain confidentiality.

Authors:  L Sweeney
Journal:  J Law Med Ethics       Date:  1997 Summer-Fall       Impact factor: 1.718

2.  Reducing the dimensionality of data with neural networks.

Authors:  G E Hinton; R R Salakhutdinov
Journal:  Science       Date:  2006-07-28       Impact factor: 47.728

3.  Protecting privacy using k-anonymity.

Authors:  Khaled El Emam; Fida Kamal Dankar
Journal:  J Am Med Inform Assoc       Date:  2008-06-25       Impact factor: 4.497

Review 4.  Identifiability in biobanks: models, measures, and mitigation strategies.

Authors:  Bradley Malin; Grigorios Loukides; Kathleen Benitez; Ellen Wright Clayton
Journal:  Hum Genet       Date:  2011-07-08       Impact factor: 4.132

5.  Urinary albumin excretion is associated with renal functional abnormalities in a nondiabetic population.

Authors:  Sara-Joan Pinto-Sietsma; Wilbert M T Janssen; Hans L Hillege; Gerjan Navis; Dick DE Zeeuw; Paul E DE Jong
Journal:  J Am Soc Nephrol       Date:  2000-10       Impact factor: 10.121

6.  DataSHIELD: resolving a conflict in contemporary bioscience--performing a pooled analysis of individual-level data without sharing the data.

Authors:  Michael Wolfson; Susan E Wallace; Nicholas Masca; Geoff Rowe; Nuala A Sheehan; Vincent Ferretti; Philippe LaFlamme; Martin D Tobin; John Macleod; Julian Little; Isabel Fortier; Bartha M Knoppers; Paul R Burton
Journal:  Int J Epidemiol       Date:  2010-07-14       Impact factor: 7.196

7.  The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies.

Authors:  Jana V van Vliet-Ostaptchouk; Marja-Liisa Nuotio; Sandra N Slagter; Dany Doiron; Krista Fischer; Luisa Foco; Amadou Gaye; Martin Gögele; Margit Heier; Tero Hiekkalinna; Anni Joensuu; Christopher Newby; Chao Pang; Eemil Partinen; Eva Reischl; Christine Schwienbacher; Mari-Liis Tammesoo; Morris A Swertz; Paul Burton; Vincent Ferretti; Isabel Fortier; Lisette Giepmans; Jennifer R Harris; Hans L Hillege; Jostein Holmen; Antti Jula; Jenny E Kootstra-Ros; Kirsti Kvaløy; Turid Lingaas Holmen; Satu Männistö; Andres Metspalu; Kristian Midthjell; Madeleine J Murtagh; Annette Peters; Peter P Pramstaller; Timo Saaristo; Veikko Salomaa; Ronald P Stolk; Matti Uusitupa; Pim van der Harst; Melanie M van der Klauw; Melanie Waldenberger; Markus Perola; Bruce Hr Wolffenbuttel
Journal:  BMC Endocr Disord       Date:  2014-02-01       Impact factor: 2.763

8.  Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays.

Authors:  Nils Homer; Szabolcs Szelinger; Margot Redman; David Duggan; Waibhav Tembe; Jill Muehling; John V Pearson; Dietrich A Stephan; Stanley F Nelson; David W Craig
Journal:  PLoS Genet       Date:  2008-08-29       Impact factor: 5.917

  8 in total

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