Literature DB >> 26034443

Rheumatoid hand surgery: is there a decline? A 22-year population-based study.

Rajiv Gogna1, Graham Cheung2, Melanie Arundell3, Chris Deighton4, Tommy R Lindau3.   

Abstract

BACKGROUND: Rheumatoid arthritis (RA) is the most common idiopathic inflammatory arthritis affecting 0.8 % of the population. It can cause significant hand and wrist damage and dysfunction. Recent advances in anti-rheumatic treatments have the potential to decrease the prevalence of hand deformities in patients with RA. Our aim was to investigate whether there has been a decline over 22-years in the number of hand surgical procedures being undertaken for patients with RA and whether this correlates with the introduction of new anti-rheumatic therapies.
METHODS: We performed a retrospective, population-based (Derbyshire) study of all patients with RA who underwent hand surgery at the Pulvertaft Hand Centre from 1990 to 2012. Index procedures included (1) teno-synovectomy and soft tissue procedures, (2) wrist arthrodesis/arthroplasty and (3) finger arthrodesis.
RESULTS: A total of 297 procedures were performed in 153 Derbyshire patients with RA over the 22-year period, with mean age at surgery 59 years (range 24-88 years). The female to male ratio was 2.5:1. The overall trend showed a peak in 2004 and a subsequent decline thereafter. This coincides with an increasing tendency by local rheumatologists to introduce earlier and more intensive conventional disease-modifying drugs and biological therapies for more resistant disease.
CONCLUSIONS: There has been a decline in the number of hand surgery procedures being performed on patients with RA during our 22-year population-based study. It indicates that medical treatments and strategies have been successful at preventing disease progression.

Entities:  

Keywords:  Biological; DMARD; Hand; Rheumatoid arthritis; Wrist

Year:  2015        PMID: 26034443      PMCID: PMC4447684          DOI: 10.1007/s11552-014-9708-9

Source DB:  PubMed          Journal:  Hand (N Y)        ISSN: 1558-9447


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