Literature DB >> 26034038

Tumor-Triggered Controlled Drug Release from Electrospun Fibers Using Inorganic Caps for Inhibiting Cancer Relapse.

Xin Zhao1, Ziming Yuan2, Lara Yildirimer3, Jingwen Zhao1, Zhi Yuan William Lin1, Zhi Cao4, Guoqing Pan1, Wenguo Cui1.   

Abstract

A smart, tumor-trigged, controlled drug release using inorganic "caps" with CO3 (2-) functional groups in electrospun fibers is presented for inhibiting cancer relapse. When the drug-loaded intelligent electrospun fibers encounter pathological acidic environments, the inorganic gates react with the acids and produce CO2 gas, which enables water penetration into the core of the fibers to induce rapid drug release.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  cancer therapy; controlled release; drug delivery, electrospun fibers; inorganic caps; tumor-triggered

Mesh：

Substances：

Year:  2015        PMID： 26034038     DOI： 10.1002/smll.201500985

Source DB:  PubMed          Journal:  Small        ISSN： 1613-6810            Impact factor:   13.281


  8 in total

1.  Electrospinning and Electrospun Nanofibers: Methods, Materials, and Applications.

Authors:  Jiajia Xue; Tong Wu; Yunqian Dai; Younan Xia
Journal:  Chem Rev       Date:  2019-03-27       Impact factor: 60.622

Review 2.  Emerging Roles of Electrospun Nanofibers in Cancer Research.

Authors:  Shixuan Chen; Sunil Kumar Boda; Surinder K Batra; Xiaoran Li; Jingwei Xie
Journal:  Adv Healthc Mater       Date:  2017-12-06       Impact factor: 9.933

3.  Tumor-triggered drug release from calcium carbonate-encapsulated gold nanostars for near-infrared photodynamic/photothermal combination antitumor therapy.

Authors:  Yanlei Liu; Xiao Zhi; Meng Yang; Jingpu Zhang; Lingnan Lin; Xin Zhao; Wenxiu Hou; Chunlei Zhang; Qian Zhang; Fei Pan; Gabriel Alfranca; Yuming Yang; Jesús M de la Fuente; Jian Ni; Daxiang Cui
Journal:  Theranostics       Date:  2017-04-10       Impact factor: 11.556

4.  Controlled and tuneable drug release from electrospun fibers and a non-invasive approach for cytotoxicity testing.

Authors:  G Piccirillo; D A Carvajal Berrio; A Laurita; A Pepe; B Bochicchio; K Schenke-Layland; S Hinderer
Journal:  Sci Rep       Date:  2019-03-05       Impact factor: 4.379

5.  Cancer cell membrane-coated mesoporous silica loaded with superparamagnetic ferroferric oxide and Paclitaxel for the combination of Chemo/Magnetocaloric therapy on MDA-MB-231 cells.

Authors:  Defu Cai; Likun Liu; Cuiyan Han; Xiaoxing Ma; Jiayi Qian; Jianwen Zhou; Wenquan Zhu
Journal:  Sci Rep       Date:  2019-10-09       Impact factor: 4.379

6.  Mechanical Properties of Electrospun, Blended Fibrinogen: PCL Nanofibers.

Authors:  Jacquelyn M Sharpe; Hyunsu Lee; Adam R Hall; Keith Bonin; Martin Guthold
Journal:  Nanomaterials (Basel)       Date:  2020-09-15       Impact factor: 5.076

7.  Human natural killer cells for targeting delivery of gold nanostars and bimodal imaging directed photothermal/photodynamic therapy and immunotherapy.

Authors:  Bin Liu; Wen Cao; Jin Cheng; Sisi Fan; Shaojun Pan; Lirui Wang; Jiaqi Niu; Yunxiang Pan; Yanlei Liu; Xiyang Sun; Lijun Ma; Jie Song; Jian Ni; Daxiang Cui
Journal:  Cancer Biol Med       Date:  2019-11       Impact factor: 4.248

8.  A tumor microenvironment responsive biodegradable CaCO3/MnO2- based nanoplatform for the enhanced photodynamic therapy and improved PD-L1 immunotherapy.

Authors:  Yanlei Liu; Yunxiang Pan; Wen Cao; Fangfang Xia; Bin Liu; Jiaqi Niu; Gabriel Alfranca; Xiyang Sun; Lijun Ma; Jesus Martinez de la Fuente; Jie Song; Jian Ni; Daxiang Cui
Journal:  Theranostics       Date:  2019-09-21       Impact factor: 11.556
  8 in total

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