Jennita Reefhuis1, Suzanne M Gilboa1, Marlene Anderka2, Marilyn L Browne3,4, Marcia L Feldkamp5, Charlotte A Hobbs6, Mary M Jenkins1, Peter H Langlois7, Kimberly B Newsome1, Andrew F Olshan8, Paul A Romitti9, Stuart K Shapira1, Gary M Shaw10, Sarah C Tinker1, Margaret A Honein1. 1. National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia. 2. Massachusetts Department of Public Health, Boston, Massachusetts. 3. New York State Department of Health, Albany, New York. 4. University at Albany School of Public Health, Rensselaer, New York. 5. University of Utah School of Medicine, Salt Lake City, Utah. 6. College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas. 7. Texas Department of State Health Services, Austin, Texas. 8. University of North Carolina, Chapel Hill, North Carolina. 9. University of Iowa, Iowa City, Iowa. 10. Stanford University School of Medicine, Stanford, California.
Abstract
BACKGROUND: The National Birth Defects Prevention Study (NBDPS) is a large population-based multicenter case-control study of major birth defects in the United States. METHODS: Data collection took place from 1998 through 2013 on pregnancies ending between October 1997 and December 2011. Cases could be live born, stillborn, or induced terminations, and were identified from birth defects surveillance programs in Arkansas, California, Georgia, Iowa, Massachusetts, New Jersey, New York, North Carolina, Texas, and Utah. Controls were live born infants without major birth defects identified from the same geographical regions and time periods as cases by means of either vital records or birth hospitals. Computer-assisted telephone interviews were completed with women between 6 weeks and 24 months after the estimated date of delivery. After completion of interviews, families received buccal cell collection kits for the mother, father, and infant (if living). RESULTS: There were 47,832 eligible cases and 18,272 eligible controls. Among these, 32,187 (67%) and 11,814 (65%), respectively, provided interview information about their pregnancies. Buccal cell collection kits with a cytobrush for at least one family member were returned by 19,065 case and 6,211 control families (65% and 59% of those who were sent a kit). More than 500 projects have been proposed by the collaborators and over 200 manuscripts published using data from the NBDPS through December 2014. CONCLUSION: The NBDPS has made substantial contributions to the field of birth defects epidemiology through its rigorous design, including case classification, detailed questionnaire and specimen collection, large study population, and collaborative activities across Centers.
BACKGROUND: The National Birth Defects Prevention Study (NBDPS) is a large population-based multicenter case-control study of major birth defects in the United States. METHODS: Data collection took place from 1998 through 2013 on pregnancies ending between October 1997 and December 2011. Cases could be live born, stillborn, or induced terminations, and were identified from birth defects surveillance programs in Arkansas, California, Georgia, Iowa, Massachusetts, New Jersey, New York, North Carolina, Texas, and Utah. Controls were live born infants without major birth defects identified from the same geographical regions and time periods as cases by means of either vital records or birth hospitals. Computer-assisted telephone interviews were completed with women between 6 weeks and 24 months after the estimated date of delivery. After completion of interviews, families received buccal cell collection kits for the mother, father, and infant (if living). RESULTS: There were 47,832 eligible cases and 18,272 eligible controls. Among these, 32,187 (67%) and 11,814 (65%), respectively, provided interview information about their pregnancies. Buccal cell collection kits with a cytobrush for at least one family member were returned by 19,065 case and 6,211 control families (65% and 59% of those who were sent a kit). More than 500 projects have been proposed by the collaborators and over 200 manuscripts published using data from the NBDPS through December 2014. CONCLUSION: The NBDPS has made substantial contributions to the field of birth defects epidemiology through its rigorous design, including case classification, detailed questionnaire and specimen collection, large study population, and collaborative activities across Centers.
Authors: Lisenka E L M Vissers; Conny M A van Ravenswaaij; Ronald Admiraal; Jane A Hurst; Bert B A de Vries; Irene M Janssen; Walter A van der Vliet; Erik H L P G Huys; Pieter J de Jong; Ben C J Hamel; Eric F P M Schoenmakers; Han G Brunner; Joris A Veltman; Ad Geurts van Kessel Journal: Nat Genet Date: 2004-08-08 Impact factor: 38.330
Authors: Margaret A Honein; Sonja A Rasmussen; Jennita Reefhuis; Paul A Romitti; Edward J Lammer; Lixian Sun; Adolfo Correa Journal: Epidemiology Date: 2007-03 Impact factor: 4.822
Authors: P W Yoon; S A Rasmussen; M C Lynberg; C A Moore; M Anderka; S L Carmichael; P Costa; C Druschel; C A Hobbs; P A Romitti; P H Langlois; L D Edmonds Journal: Public Health Rep Date: 2001 Impact factor: 2.792
Authors: M García-Closas; K M Egan; J Abruzzo; P A Newcomb; L Titus-Ernstoff; T Franklin; P K Bender; J C Beck; L Le Marchand; A Lum; M Alavanja; R B Hayes; J Rutter; K Buetow; L A Brinton; N Rothman Journal: Cancer Epidemiol Biomarkers Prev Date: 2001-06 Impact factor: 4.254
Authors: Laura J Lee; Elaine Symanski; Philip J Lupo; Sarah C Tinker; Hilda Razzaghi; Lisa A Pompeii; Adrienne T Hoyt; Mark A Canfield; Wenyaw Chan Journal: Am J Ind Med Date: 2015-12-17 Impact factor: 2.214
Authors: Shao Lin; Ziqiang Lin; Yanqiu Ou; Aida Soim; Srishti Shrestha; Yi Lu; Scott Sheridan; Thomas J Luben; Edward Fitzgerald; Erin Bell; Gary M Shaw; Jennita Reefhuis; Peter H Langlois; Paul Romitti; Marcia L Feldkamp; Sadia Malik; Cristian Pantea; Seema Nayak; Syni-An Hwang; Marilyn Browne Journal: Environ Int Date: 2018-06-08 Impact factor: 9.621
Authors: Karrie F Downing; Tiffany Riehle-Colarusso; Suzanne M Gilboa; Angela E Lin; Matthew E Oster; Sarah C Tinker; Sherry L Farr Journal: Cardiol Young Date: 2019-06-04 Impact factor: 1.093
Authors: Marisa A Ryan; Andrew F Olshan; Mark A Canfield; Adrienne T Hoyt; Angela E Scheuerle; Suzan L Carmichael; Gary M Shaw; Martha M Werler; Sarah C Fisher; Tania A Desrosiers Journal: Int J Pediatr Otorhinolaryngol Date: 2019-03-23 Impact factor: 1.675
Authors: Nelson D Pace; Tania A Desrosiers; Suzan L Carmichael; Gary M Shaw; Andrew F Olshan; Anna Maria Siega-Riz Journal: Paediatr Perinat Epidemiol Date: 2017-09-04 Impact factor: 3.980
Authors: Giehae Choi; Jeanette A Stingone; Tania A Desrosiers; Andrew F Olshan; Wendy N Nembhard; Gary M Shaw; Shannon Pruitt; Paul A Romitti; Mahsa M Yazdy; Marilyn L Browne; Peter H Langlois; Lorenzo Botto; Thomas J Luben Journal: Environ Res Date: 2019-09-10 Impact factor: 6.498
Authors: Cara T Mai; Jennifer Isenburg; Peter H Langlois; C J Alverson; Suzanne M Gilboa; Russel Rickard; Mark A Canfield; Suzanne B Anjohrin; Philip J Lupo; Deanna R Jackson; Erin B Stallings; Angela E Scheuerle; Russell S Kirby Journal: Birth Defects Res A Clin Mol Teratol Date: 2015-11