Literature DB >> 26033591

Involvement of PI3K, MAPK ERK1/2 and p38 in Functional Stimulation of Mesenchymal Progenitor Cells by Alkaloid Songorine.

G N Zyuz'kov1, V V Zhdanov, L A Miroshnichenko, E V Udut, A V Chaikovskii, E V Simanina, M G Danilets, M Yu Minakova, V V Udut, T G Tolstikova, E E Shults, L A Stavrova, Ya V Burmina, A M Dygai.   

Abstract

We studied the role of intracellular signaling molecules PI3K, МАРK ERK1/2, and р38 in stimulation of realization of the growth potential of mesenchymal progenitor cells by alkaloid songorine in vitro. Inhibitors of PI3K, ERK1/2 and р38 canceled the increase in proliferative activity of progenitor cells, the blockers of ERK1/2 and р38 reduced the intensity of progenitor cell differentiation.

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Year:  2015        PMID: 26033591     DOI: 10.1007/s10517-015-2889-6

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  3 in total

1.  The Role of Intracellular Signaling Molecules in the Production of Granulocytic CSF Mononuclear Phagocytes in Stress and Cytostatic Influence.

Authors:  V V Zhdanov; L A Miroshnichenko; G N Zyuz'kov; T Yu Khrichkova; E V Udut; E V Simanina; E Yu Sherstoboev; L A Stavrova; V I Agafonov; M G Danilets; E S Trofimova; M Yu Minakova; A M Dygai
Journal:  Bull Exp Biol Med       Date:  2021-09-20       Impact factor: 0.804

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Authors:  Haixia Wang; Hongbin Mou; Xiaolan Xu; Changhua Liu; Gang Zhou; Bo Gao
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269

3.  Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.

Authors:  Fu Peng; Nan Zhang; Chunting Wang; Xiaoyun Wang; Wei Huang; Cheng Peng; Gu He; Bo Han
Journal:  Cell Prolif       Date:  2019-10-27       Impact factor: 6.831

  3 in total

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