Federico Perrone1, Emanuela Bianciardi2, Domenico Benavoli3, Valeria Tognoni4, Cinzia Niolu5, Alberto Siracusano6, Achille L Gaspari7, Paolo Gentileschi8,9. 1. General Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Italy. fed.perrone@gmail.com. 2. Psychiatric Unit, Department of System Medicine, University of Rome, Tor Vergata, Italy. emanuelabianciardi@libero.it. 3. General Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Italy. dobenavoli@yahoo.com. 4. General Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Italy. vtognoni@gmail.com. 5. Psychiatric Unit, Department of System Medicine, University of Rome, Tor Vergata, Italy. niolu@med.uniroma2.it. 6. Psychiatric Unit, Department of System Medicine, University of Rome, Tor Vergata, Italy. siracusano@med.uniroma2.it. 7. General Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Italy. gaspari@med.uniroma2.it. 8. General Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Italy. gentilp@yahoo.com. 9. Bariatric Surgery Unit, Department of Experimental Medicine and Surgery, University of Rome, Tor Vergata, Italy. gentilp@yahoo.com.
Abstract
BACKGROUND: Gender might be important in predicting outcomes after bariatric surgery. The aim of the study was to investigate the influence of gender on long-term weight loss and comorbidity improvement after laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB). METHODS: A cohort of 304 consecutive patients underwent surgery in 2006-2009: 162 (98 women, 64 men) underwent LSG and 142 (112 women, 30 men) underwent LRYGB. The mean follow-up time was 75.8 ± 8.4 months (range, 60-96 months). RESULTS: Overall mean (95% CI) reduction in BMI was 23.5 (24.3-22.7) kg/m(2) after 5 years, with no statistical difference between LSG and LRYGB groups (P = 0.94). The overall means ± standard deviations of %EBMIL after 5 years were 78.8 ± 23.5 and 81.6 ± 21.4 in the LSG and LRYGB groups, respectively. Only for LSG group %EBMIL after 24-36 and 60 months differed significantly between male and female patients (P = 0.003 versus P = 0.06 in LRYGB), and 89 versus 90% of patients showed improvements in comorbidities in the LSG and LRYGB groups, respectively. Only two patients (women) were lost to follow-up: 1/162 (0.6%) for LSG at the 4th year and 1/142 (0.7%) for LRYGB to the 5th year. CONCLUSIONS: LSG was more effective in obese male than in female patients in terms of %EBMIL, with no difference in comorbidities. LRYGB elicited similar results in both genders in terms of %EBMIL and comorbidities.
BACKGROUND: Gender might be important in predicting outcomes after bariatric surgery. The aim of the study was to investigate the influence of gender on long-term weight loss and comorbidity improvement after laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB). METHODS: A cohort of 304 consecutive patients underwent surgery in 2006-2009: 162 (98 women, 64 men) underwent LSG and 142 (112 women, 30 men) underwent LRYGB. The mean follow-up time was 75.8 ± 8.4 months (range, 60-96 months). RESULTS: Overall mean (95% CI) reduction in BMI was 23.5 (24.3-22.7) kg/m(2) after 5 years, with no statistical difference between LSG and LRYGB groups (P = 0.94). The overall means ± standard deviations of %EBMIL after 5 years were 78.8 ± 23.5 and 81.6 ± 21.4 in the LSG and LRYGB groups, respectively. Only for LSG group %EBMIL after 24-36 and 60 months differed significantly between male and female patients (P = 0.003 versus P = 0.06 in LRYGB), and 89 versus 90% of patients showed improvements in comorbidities in the LSG and LRYGB groups, respectively. Only two patients (women) were lost to follow-up: 1/162 (0.6%) for LSG at the 4th year and 1/142 (0.7%) for LRYGB to the 5th year. CONCLUSIONS: LSG was more effective in obese male than in female patients in terms of %EBMIL, with no difference in comorbidities. LRYGB elicited similar results in both genders in terms of %EBMIL and comorbidities.
Authors: Manish M Tiwari; Matthew R Goede; Jason F Reynoso; Albert W Tsang; Dmitry Oleynikov; Corrigan L McBride Journal: Surg Obes Relat Dis Date: 2011-02-24 Impact factor: 4.734
Authors: Sarah Ying Tse Tan; Nicholas L Syn; Daryl J Lin; Chin Hong Lim; Sonali Ganguly; Hock Soo Ong; Jeremy Tian Hui Tan; Phong Ching Lee Journal: Obes Surg Date: 2021-08-06 Impact factor: 4.129