Literature DB >> 26032296

Excessive pediatric fasciitis necrotisans due to Pseudomonas aeruginosa infection successfully treated with negative pressure wound therapy.

Levente Szabó1, István Szegedi1, Csongor Kiss1, Edit Szikszay1, Éva Remenyik2, István Csízy1, István Juhász2,3.   

Abstract

The case of a 10-year old female child is described with a history of myeloproliferative disorder having skin, bone and visceral involvement. Bone marrow biopsy revealed histiocytosis X. During chemotherapy necrotizing fasciitis of the lower abdominal wall was diagnosed. Multiple microbiological cultures taken from the wound base revealed Pseudomonas aeruginosa infection. Surgical necrectomy and application of negative pressure wound therapy (NPWT) was started together with intensive care treatment for sepsis. As both wound and general condition of the patient improved, autologous split thickness skin grafting was carried out in two sitting under continuing NPWT application. The applied skin grafts showed excellent take, the perilesional subcutaneous recesses resolved and complete healing was achieved after 28 days of NPWT treatment. Proper dermatological diagnosis and immediate escharectomy complemented with application of NPWT can be life-saving in the treatment of necrotizing fasciitis.
© 2015 Wiley Periodicals, Inc.

Entities:  

Keywords:  Pseudomonas aeruginosa infection; fasciitis necrotisans; histiocytosis X; life-saving; negative pressure wound therapy; pediatric case

Mesh:

Year:  2015        PMID: 26032296     DOI: 10.1111/dth.12252

Source DB:  PubMed          Journal:  Dermatol Ther        ISSN: 1396-0296            Impact factor:   2.851


  5 in total

Review 1.  Negative-Pressure Wound Therapy in Infants and Children: A Population-Based Study.

Authors:  Katherine B Santosa; Matt Keller; Margaret A Olsen; Alexandra M Keane; Erika D Sears; Alison K Snyder-Warwick
Journal:  J Surg Res       Date:  2018-11-30       Impact factor: 2.192

2.  Pediatric Necrotizing Fasciitis: Restitutio Ad Integrum after Early Diagnosis and Aggressive Surgical Treatment.

Authors:  Angela Lemaréchal; Sabine Zundel; Philipp Szavay
Journal:  European J Pediatr Surg Rep       Date:  2016-11-28

3.  Necrotizing fasciitis after scrotum skin injury in an infant: A case report.

Authors:  Z X Ren; C L Liu; Q Zhang; F Xu; Y N Zheng; X J Li; J Yang
Journal:  Medicine (Baltimore)       Date:  2018-03       Impact factor: 1.889

4.  Successful Use of Negative-pressure Wound Therapy and Dermal Substitute in the Treatment of Gluteal Ecthyma Gangrenosum in a 2-year-old Girl.

Authors:  Giorgio Persano; Enrico Pinzauti; Simone Pancani; Filippo Incerti
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-10-03

5.  Necrotizing fasciitis of the neck and head complicated with chronic osteomyelitis: Case report presentation.

Authors:  Rosa María Wong-Chew; Antonio H Angel-Ambrocio; Sheila Yadira Gomez-Murillo; Angel Puente-Sanchez; Gerardo Fernandez-Sobrino; Alfonso Marhx-Bracho; María de Lourdes Marroquín-Yañez
Journal:  Int J Surg Case Rep       Date:  2019-03-26
  5 in total

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