| Literature DB >> 26032296 |
Levente Szabó1, István Szegedi1, Csongor Kiss1, Edit Szikszay1, Éva Remenyik2, István Csízy1, István Juhász2,3.
Abstract
The case of a 10-year old female child is described with a history of myeloproliferative disorder having skin, bone and visceral involvement. Bone marrow biopsy revealed histiocytosis X. During chemotherapy necrotizing fasciitis of the lower abdominal wall was diagnosed. Multiple microbiological cultures taken from the wound base revealed Pseudomonas aeruginosa infection. Surgical necrectomy and application of negative pressure wound therapy (NPWT) was started together with intensive care treatment for sepsis. As both wound and general condition of the patient improved, autologous split thickness skin grafting was carried out in two sitting under continuing NPWT application. The applied skin grafts showed excellent take, the perilesional subcutaneous recesses resolved and complete healing was achieved after 28 days of NPWT treatment. Proper dermatological diagnosis and immediate escharectomy complemented with application of NPWT can be life-saving in the treatment of necrotizing fasciitis.Entities:
Keywords: Pseudomonas aeruginosa infection; fasciitis necrotisans; histiocytosis X; life-saving; negative pressure wound therapy; pediatric case
Mesh:
Year: 2015 PMID: 26032296 DOI: 10.1111/dth.12252
Source DB: PubMed Journal: Dermatol Ther ISSN: 1396-0296 Impact factor: 2.851